100-02-7|4-NitrophenolProducts Supply - Chemical intermediates Network

4-Nitrophenol cas no:100-02-7

Synonyms: P-Nitro phenol; P-Nitrophenol;

Identification

Name4-Nitrophenol
CAS100-02-7
SynonymsP-Nitro phenol; P-Nitrophenol;
EINECS(EC#)202-811-7
Molecular FormulaC6H5NO3
Molecular Weight139.11

Chemical Properties

Appearanceyellow to brown crystals
storage tempStore in dark!
Sensitive Light Sensitive

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1

Safety Data

Hazard Xn:Harmful
Risk R20/21/22;R33
Safety

Poison by ingestion, subcutaneous, intraperitoneal, intravenous, and intramuscular routes. Moderately toxic by skin contact. Human mutation data reported. Its exothermic decomposition causes a dangerously fast pressure increase. Mixtures with diethyl phosphite may explode when heated. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: Harmful Xn, Toxic T, Flammable F
Risk Statements: 20/21/22-33-39/23/24/25-23/24/25-11
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R33:Danger of cumulative effects.
R39:Danger of very serious irreversible effects.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R11:Highly flammable.
Safety Statements: 28-28A-45-36/37-16-7
S28:After contact with skin, wash immediately with plenty of soap-suds.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37:Wear suitable protective clothing and gloves.
S16:Keep away from sources of ignition.
S7:Keep container tightly closed.
RIDADR: UN 1663 6.1/PG 3
WGK Germany: 2
RTECS: SM2275000
HazardClass: 6.1
PackingGroup of 4-Nitrophenol (CAS NO.100-02-7): III

HS Code 29089000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	unreported	150mg/kg (150mg/kg)		"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 97, 1971.
dog	LDLo	intravenous	10mg/kg (10mg/kg)		U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 131, 1941.
frog	LDLo	subcutaneous	60mg/kg (60mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA	Revue Medicale de la Suisse Romande. Vol. 16, Pg. 449, 1896.
guinea pig	LD50	skin	> 1gm/kg (1000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	National Technical Information Service. Vol. OTS0570918,
guinea pig	LDLo	subcutaneous	200mg/kg (200mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: COMA	Revue Medicale de la Suisse Romande. Vol. 16, Pg. 449, 1896.
mammal (species unspecified)	LD50	oral	247mg/kg (247mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(10), Pg. 16, 1980.
mammal (species unspecified)	LD50	skin	920mg/kg (920mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(10), Pg. 16, 1980.
mammal (species unspecified)	LD50	unreported	175mg/kg (175mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(11), Pg. 13, 1974.
mouse	LD50	intracrebral	90mg/kg (90mg/kg)		Pesticide Biochemistry and Physiology. Vol. 8, Pg. 302, 1978.
mouse	LD50	intraperitoneal	75mg/kg (75mg/kg)		National Technical Information Service. Vol. AD691-490,
mouse	LD50	oral	282mg/kg (282mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	National Technical Information Service. Vol. OTS0570918,
pigeon	LDLo	intramuscular	65mg/kg (65mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 49, Pg. 187, 1933.
rabbit	LDLo	oral	600mg/kg (600mg/kg)	GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BEHAVIORAL: ATAXIA	National Technical Information Service. Vol. 0TS0518150,
rabbit	LDLo	skin	1500mg/kg (1500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS	National Technical Information Service. Vol. 0TS0518150,
rat	LD50	oral	202mg/kg (202mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	National Technical Information Service. Vol. 0TS0518152,
rat	LD50	skin	1024mg/kg (1024mg/kg)		National Technical Information Service. Vol. 0TS0516686,
rat	LDLo	subcutaneous	200mg/kg (200mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: COMA	Revue Medicale de la Suisse Romande. Vol. 16, Pg. 449, 1896.

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4-Nitrophenol cas no:100-02-7

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