Benzenecarboximidamide,4,4'-[1,5-pentanediylbis(oxy)]bis- cas no:100-33-4
Synonyms: Benzamidine,4,4'-(pentamethylenedioxy)di- (6CI,7CI,8CI);4,4'-(Pentamethylenedioxy)dibenzamidine;4,4'-Diamidino-a,w-diphenoxypentane;MP 601205;NSC 9921;Pentamidine;p,p'-(Pentamethylenedioxy)dibenzamidine;
NameBenzenecarboximidamide,4,4'-[1,5-pentanediylbis(oxy)]bis-
CAS100-33-4
SynonymsBenzamidine,4,4'-(pentamethylenedioxy)di- (6CI,7CI,8CI);4,4'-(Pentamethylenedioxy)dibenzamidine;4,4'-Diamidino-a,w-diphenoxypentane;MP 601205;NSC 9921;Pentamidine;p,p'-(Pentamethylenedioxy)dibenzamidine;
EINECS(EC#)202-841-0
Molecular FormulaC19H24N4O2
Molecular Weight340.47
AppearanceOrange solid.
storage tempStore in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety
Poison by intraperitoneal route. Human systemic effects by intramuscular and parenteral routes: anesthesia, changes in kidney tubules, fever, and convulsions. When heated to decomposition it emits toxic fumes of NOx.
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III
Hazardous Substances Data: 100-33-4(Hazardous Substances Data)
| mammal (species unspecified) |
LD50 |
subcutaneous |
100mg/kg (100mg/kg) |
|
Bulletin de la Societe Chimique de France. Vol. -, Pg. 376, 1968. |
| man |
TDLo |
intramuscular |
28mg/kg/1W-I (28mg/kg) |
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" |
Archives of Internal Medicine. Vol. 145, Pg. 2247, 1985.
|
| man |
TDLo |
parenteral |
4mg/kg/3D (4mg/kg) |
BEHAVIORAL: GENERAL ANESTHETIC
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Lancet. Vol. 246, Pg. 338, 1944. |
| mouse |
LD50 |
intraperitoneal |
50mg/kg (50mg/kg) |
|
Journal of Medicinal Chemistry. Vol. 18, Pg. 794, 1975. |
| women |
TDLo |
parenteral |
4mg/kg (4mg/kg) |
ENDOCRINE: HYPOGLYCEMIA |
Annals of Internal Medicine. Vol. 99, Pg. 128, 1983. |
