phenyl hydrazine cas no:100-63-0

Namephenyl hydrazine
CAS100-63-0
SynonymsHydrazinobenzene;Monophenylhydrazine;AI3-15399;BRN 0606080;CCRIS 511;Fenilidrazina;Fenilidrazina [Italian];Fenylhydrazine;Fenylhydrazine [Dutch];HSDB 1117;Hydrazine, phenyl-;Hydrazine-benzene;Hydrazobenzene;Phenylhydrazin;Phenylhydrazin [German];Phenylhydrazine [UN2572] [Poison];Phenylhydrazine and its salts;UN2572;
EINECS(EC#)202-873-5
Molecular FormulaC6H8N2
Molecular Weight108.14

Appearanceyellow to pale brown oily liquid
refractive index1.604-1.609
storage tempStore at RT.
Sensitive Air & Light Sensitive

Hazardclass6.1

Hazard T:Toxic;N:Dangerousfortheenvironment;
Risk R23/24/25;R36/38;R43;R45;R48/23/24/25;R50;R68
Safety

Hazard Codes of Phenylhydrazine (CAS NO.100-63-0):?T,N
Risk Statements: 45-23/24/25-36/38-43-48-50-68?
R45: May cause cancer.?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.?
R36/38: Irritating to eyes and skin.?
R43: May cause sensitization by skin contact.?
R48: Danger of serious damage to health by prolonged exposure.?
R50: Very toxic to aquatic organisms.?
R68: Possible risk of irreversible effects.
Safety Statements: 53-45-61?
S53: Avoid exposure - obtain special instructions before use.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 2572 6.1/PG 2
WGK Germany: 3
RTECS: MV8925000
F: 8-10-23
HazardClass: 6.1
PackingGroup: II
Confirmed carcinogen with experimental carcinogenic data. Poison by ingestion, subcutaneous, and intravenous routes. Experimental reproductive effects. Mutation data reported. Ingestion or subcutaneous injection can cause hemolysis of red blood cells. Other effects are damage to the spleen, liver, kidneys, and bone marrow. The most common effect of occupational exposure is the development of dermatitis, which, in sensitized persons, may be quite severe. Systemic effects include anemia and general weakness, gastrointestinal disturbances, and injury to the kidneys. Flammable when exposed to heat, flame, or oxidizers. To fight fire, use alcohol foam. Violent reaction with 2-phenylamino-3-phenyloxazirane. Reacts with perchloryl fluoride to form an explosive product. Vigorous reaction with lead(IV) oxide. Used as a chemical reagent, in organic synthesis, and in the manufacture of dyes and drugs. Dangerous; when heated to decomposition it emits highly toxic fumes of NO_x; can react with oxidizing materials.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	120mg/kg (120mg/kg)	?	U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 159, 1941.
dog	LDLo	oral	200mg/kg (200mg/kg)	?	U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 159, 1941.
frog	LDLo	unreported	300mg/kg (300mg/kg)	?	U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 159, 1941.
guinea pig	LD50	oral	80mg/kg (80mg/kg)	BEHAVIORAL: EXCITEMENT BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Hygiene and Sanitation Vol. 30(7-9), Pg. 191, 1965.
mouse	LC50	inhalation	2120mg/m3 (2120mg/m3)	?	Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. Vol. 115, Pg. 59, 1977.
mouse	LD50	intraperitoneal	170mg/kg (170mg/kg)	?	Cancer Research. Vol. 41, Pg. 1469, 1981.
mouse	LD50	oral	175mg/kg (175mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 30(8), Pg. 21, 1965.
mouse	LDLo	subcutaneous	170mg/kg (170mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Journal of Industrial Hygiene and Toxicology. Vol. 18, Pg. 1, 1936.
rabbit	LD50	oral	80mg/kg (80mg/kg)	BEHAVIORAL: EXCITEMENT BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Hygiene and Sanitation Vol. 30(7-9), Pg. 191, 1965.
rabbit	LDLo	skin	90mg/kg (90mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION KIDNEY, URETER, AND BLADDER: HEMATURIA	National Technical Information Service. Vol. OTS0546542,
rat	LC50	inhalation	2610mg/m3 (2610mg/m3)	?	Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. Vol. 115, Pg. 59, 1977.
rat	LD50	oral	188mg/kg (188mg/kg)	BEHAVIORAL: EXCITEMENT BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Hygiene and Sanitation Vol. 30(7-9), Pg. 191, 1965.