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Piperidine, 1-nitroso- cas no:100-75-4

Synonyms: 1-Nitrosopiperidine;N-Nitrosopiperidine; NPI; NPIP; NSC 138

Identification
NamePiperidine, 1-nitroso-
CAS100-75-4
Synonyms1-Nitrosopiperidine;N-Nitrosopiperidine; NPI; NPIP; NSC 138
EINECS(EC#)202-886-6
Molecular FormulaC5H10 N2 O
Molecular Weight114.17
Chemical Properties
Appearancelight yellow oily liquid
refractive index1.55
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T: Toxic;F: Flammable;
Risk R25
Safety

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Hazard Codes of N-Nitrosopiperidine (CAS NO.100-75-4): ToxicT,FlammableF
Risk Statements: 25-40-39/23/24/25-23/24/25-11 
R11:Highly flammable. 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R25 :Toxic if swallowed. 
R39:Danger of very serious irreversible effects. 
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 53-23-26-36/37/39-45-36/37-16-9 
S9:Keep container in a well-ventilated place. 
S16:Keep away from sources of ignition. 
S23:Do not breathe vapour. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37:Wear suitable protective clothing and gloves. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S53:Avoid exposure - obtain special instructions before use.


Toxicity
1.    

trn-dmg-orl 425 ppm

    ENMUDM    Environmental Mutagenesis. 7 (1985),349.
2.    

sce-hmn:lym 10 mmol/L

    TCMUE9    Topics in Chemical Mutagenesis. 1 (1984),129.
3.    

scu-ham TDLo:100 mg/kg (14D preg):NEO,TER

    ZKKOBW    Zeitschrift fuer Krebsforschung und Klinische Onkologie. 90 (1977),71.
4.    

orl-rat LD50:200 mg/kg

    ZEKBAI    Zeitschrift fuer Krebsforschung. 69 (1967),103.
5.    

scu-rat LD50:100 mg/kg

    ZKKOBW    Zeitschrift fuer Krebsforschung und Klinische Onkologie. 80 (1973),17.
6.    

ivn-rat LD50:60 mg/kg

    ZEKBAI    Zeitschrift fuer Krebsforschung. 69 (1967),103.
7.    

orl-ham LD50:617 mg/kg

    CALEDQ    Cancer Letters (Shannon, Ireland). 21 (1983),219.
8.    

scu-ham LD50:324 mg/kg

    ZKKOBW    Zeitschrift fuer Krebsforschung und Klinische Onkologie. 81 (1974),251.

supplier list

TECHLAB SA
Tel:(33) 03 87 75 54 29
Address: France
Shanghai Hope Chem Co., Ltd.
Tel:86-21-61723543
Address: Room508, Building1, No.88 CaiLun Road Zhangjiang H
Hangzhou J&H Chemical Co., Ltd
Tel:86-571-87396430
Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

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