Solketal cas no:100-79-8
Synonyms: (4RS)-2,2-Dimethyl-1,3-dioxolane-4-methanol;(RS)-Solketal;1,2-Isopropylideneglycerin;1,2-Isopropylideneglycerol;1,2-O,O-Isopropylideneglycerin;1,2-O-Isopropylideneglycerol;2,2-Dimethyl-1,3-dioxolan-4-methanol;2,2-Dimethyl-1,3-dioxolan-4-ylmethanol;2,2-Dimethyl-1,3-dioxolane-4-methanol;2,2-Dimethyl-1,3-dioxolane-5-methanol;2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolan;2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane;2,2-Dimethyl-4-hydroxymethyldioxolane;2,2-Dimethyl-5-hydroxymethyl-1,3-dioxolane;2,3-(Isopropylidenedioxy)propanol;2,3-Isopropylideneglycerol;2,3-O-Isopropylideneglycerol;2-Dimethyl-4-oxymethyl-1,3-dioxolane;4-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxolane;Acetone glycerin ketal;Acetoneglyceryl acetal;Acetone monoglycerol ketal;DL-Isopropylideneglycerol;GIE;Glycerin acetone ketal;Glycerin isopropylidene ether;Glycerol acetonide;Glycerol dimethylketal;Glycerol a,b-isopropylidene ether;Glycerolacetone;Isopropylidene glycerol;NSC 59720;Racemic solketal;a,b-Isopropylideneglycerol;
NameSolketal
CAS100-79-8
Synonyms(4RS)-2,2-Dimethyl-1,3-dioxolane-4-methanol;(RS)-Solketal;1,2-Isopropylideneglycerin;1,2-Isopropylideneglycerol;1,2-O,O-Isopropylideneglycerin;1,2-O-Isopropylideneglycerol;2,2-Dimethyl-1,3-dioxolan-4-methanol;2,2-Dimethyl-1,3-dioxolan-4-ylmethanol;2,2-Dimethyl-1,3-dioxolane-4-methanol;2,2-Dimethyl-1,3-dioxolane-5-methanol;2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolan;2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane;2,2-Dimethyl-4-hydroxymethyldioxolane;2,2-Dimethyl-5-hydroxymethyl-1,3-dioxolane;2,3-(Isopropylidenedioxy)propanol;2,3-Isopropylideneglycerol;2,3-O-Isopropylideneglycerol;2-Dimethyl-4-oxymethyl-1,3-dioxolane;4-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxolane;Acetone glycerin ketal;Acetoneglyceryl acetal;Acetone monoglycerol ketal;DL-Isopropylideneglycerol;GIE;Glycerin acetone ketal;Glycerin isopropylidene ether;Glycerol acetonide;Glycerol dimethylketal;Glycerol a,b-isopropylidene ether;Glycerolacetone;Isopropylidene glycerol;NSC 59720;Racemic solketal;a,b-Isopropylideneglycerol;
EINECS(EC#)202-888-7
Molecular FormulaC6H12O3
Molecular Weight132.16
Appearanceclear colourless liquid
refractive index1.433-1.435
storage temp2-8°C
Hazard Xi: Irritant;
Risk R36/37/38
Safety
A poison by intravenous route. An eye irritant. Mutation data reported. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and fumes.
Safety Information of Dioxolan (CAS NO.100-79-8):
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 23-24/25-36-26
S23:Do not breathe vapour.
S24/25:Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 2
RTECS: JI0400000
F: 10
HS Code 29329970
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| rabbit |
LDLo |
intravenous |
8530ug/kg (8.53mg/kg) |
CARDIAC: CHANGE IN RATE
VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION |
Drugs under Experimental and Clinical Research. Vol. 9, Pg. 895, 1983. |
| rat |
LD50 |
intraperitoneal |
3gm/kg (3000mg/kg) |
|
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 820, 1989. |
| rat |
LD50 |
oral |
7gm/kg (7000mg/kg) |
|
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 820, 1989. |
| rat |
LDLo |
intravenous |
3740ug/kg (3.74mg/kg) |
CARDIAC: CHANGE IN RATE
VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION |
Drugs under Experimental and Clinical Research. Vol. 9, Pg. 895, 1983. |
