10040-45-6|Sodium picosulfateProducts Supply - Chemical intermediates Network

Sodium picosulfate cas no:10040-45-6

Synonyms: Phenol,4,4'-(2-pyridinylmethylene)bis-, bis(hydrogen sulfate) (ester), disodium salt(9CI);Phenol, 4,4'-(2-pyridylmethylene)di-, bis(hydrogen sulfate) (ester)disodium salt (8CI);4,4'-(2-Pyridylmethylene)diphenol bis(hydrogen sulfate)disodium salt;DA 1773;Disodium bis[4-[(hydroxysulfonyl)oxy]phenyl](2-pyridyl)methane;Evacuol;Guttalax;Guttalax-Fher;LA 391;Laxoberal;Laxoberon;Neopax;Pico-Salax;Picolax;Picosulfate sodium;Picosulfol;Rapilax;Sodiumpicosulfate;

Identification

NameSodium picosulfate
CAS10040-45-6
SynonymsPhenol,4,4'-(2-pyridinylmethylene)bis-, bis(hydrogen sulfate) (ester), disodium salt(9CI);Phenol, 4,4'-(2-pyridylmethylene)di-, bis(hydrogen sulfate) (ester)disodium salt (8CI);4,4'-(2-Pyridylmethylene)diphenol bis(hydrogen sulfate)disodium salt;DA 1773;Disodium bis[4-[(hydroxysulfonyl)oxy]phenyl](2-pyridyl)methane;Evacuol;Guttalax;Guttalax-Fher;LA 391;Laxoberal;Laxoberon;Neopax;Pico-Salax;Picolax;Picosulfate sodium;Picosulfol;Rapilax;Sodiumpicosulfate;
EINECS(EC#)233-120-9
Molecular FormulaC₁₈H₁₃NNa₂O₈S₂
Molecular Weight499.42

Chemical Properties

Appearancegray powder complex

Safety Data

Safety Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. A cathartic. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	2900mg/kg (2900mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 341, 1977.
mouse	LD50	intravenous	1600mg/kg (1600mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 341, 1977.
mouse	LD50	oral	14500mg/kg (14500mg/kg)	BEHAVIORAL: ATAXIA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 341, 1977.
mouse	LD50	subcutaneous	6420mg/kg (6420mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Nara Igaku Zasshi. Journal of the Nara Medical Association. Vol. 28, Pg. 258, 1977.
rat	LD50	intraperitoneal	3gm/kg (3000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 341, 1977.
rat	LD50	intravenous	1450mg/kg (1450mg/kg)	BEHAVIORAL: ATAXIA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 341, 1977.
rat	LD50	oral	11300mg/kg (11300mg/kg)		Drugs in Japan Vol. -, Pg. 993, 1995.
rat	LD50	subcutaneous	6980mg/kg (6980mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: COMA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Nara Igaku Zasshi. Journal of the Nara Medical Association. Vol. 28, Pg. 258, 1977.

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Sodium picosulfate cas no:10040-45-6

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