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7H-Furo[3',2':4,5]furo[2,3-c]xanthen-7-one,3a,12c-dihydro-8-hydroxy-6-methoxy-, (3aR,12cS)- cas no:10048-13-2

Synonyms: 7H-Furo[3',2':4,5]furo[2,3-c]xanthen-7-one,3a,12c-dihydro-8-hydroxy-6-methoxy- (7CI,8CI);7H-Furo[3',2':4,5]furo[2,3-c]xanthen-7-one,3a,12c-dihydro-8-hydroxy-6-methoxy-, (3aR-cis)-;Sterigmatocystin (6CI);NSC201423;NSC 204985;Sterigmatocystine;

Identification
Name7H-Furo[3',2':4,5]furo[2,3-c]xanthen-7-one,3a,12c-dihydro-8-hydroxy-6-methoxy-, (3aR,12cS)-
CAS10048-13-2
Synonyms7H-Furo[3',2':4,5]furo[2,3-c]xanthen-7-one,3a,12c-dihydro-8-hydroxy-6-methoxy- (7CI,8CI);7H-Furo[3',2':4,5]furo[2,3-c]xanthen-7-one,3a,12c-dihydro-8-hydroxy-6-methoxy-, (3aR-cis)-;Sterigmatocystin (6CI);NSC201423;NSC 204985;Sterigmatocystine;
EINECS(EC#)233-158-6
Molecular FormulaC18H12O6
Molecular Weight328.34
Chemical Properties
AppearancePale yellow solid.
refractive index1.686
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T: Toxic;
Risk R25
Safety

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Poison by ingestion and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
 

Hazard Codes of Sterigmatocystin (CAS NO.10048-13-2): ToxicT
Risk Statements: 25-40
R25 :Toxic if swallowed. 
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 36/37-45
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)


Toxicity
1.    

dnr-bcs 10 µg/disc

    MUREAV    Mutation Research. 97 (1982),339.
2.    

dns-hmn:hla 1 µmol/L

    CNREA8    Cancer Research. 38 (1978),2621.
3.    

msc-hmn:emb 100 µg/L

    KIKNAJ    Kokuritsu Idengaku Kenkyusho Nempo. Annual Report of the National Institute of Genetics.(29)(1978),38.
4.    

orl-rat TDLo:175 mg/kg/52W-C:CAR

    FCTXAV    Food and Cosmetics Toxicology. 8 (1970),289.
5.    

skn-rat TDLo:560 mg/kg/70W-I:CAR

    TXAPA9    Toxicology and Applied Pharmacology. 26 (1973),274.
6.    

orl-rat LD50:120 mg/kg

    FCTXAV    Food and Cosmetics Toxicology. 7 (1969),135.
7.    

ipr-rat LD50:65 mg/kg

    FCTXAV    Food and Cosmetics Toxicology. 7 (1969),135.
8.    

orl-mus LD50:800 mg/kg

    MMAPAP    Mycopathologia et Mycologia Applicata. 35 (1968),373.
9.    

orl-mky LD50:32 mg/kg

    BJEPA5    British Journal of Experimental Pathology. 51 (1970),183.

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