Benzeneacetic acid, a-(hydroxymethyl)-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (aS)- cas no:101-31-5
Synonyms: 1aH,5aH-Tropan-3a-ol, (-)-tropate (ester) (8CI);Benzeneacetic acid, a-(hydroxymethyl)-,8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-;Tropic acid, 1aH,5aH-tropan-3a-yl ester, (-)- (8CI);(-)-Atropine;(-)-Hyoscyamine;(S)-(-)-Hyoscyamine;(S)-Atropine;1aH,5aH-Tropan-3a-yl (-)-tropate;Cystospaz;Daturine;Duboisine;Hyoscyamine;L-Hyoscyamin;l-Atropine;
NameBenzeneacetic acid, a-(hydroxymethyl)-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (aS)-
CAS101-31-5
Synonyms1aH,5aH-Tropan-3a-ol, (-)-tropate (ester) (8CI);Benzeneacetic acid, a-(hydroxymethyl)-,8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-;Tropic acid, 1aH,5aH-tropan-3a-yl ester, (-)- (8CI);(-)-Atropine;(-)-Hyoscyamine;(S)-(-)-Hyoscyamine;(S)-Atropine;1aH,5aH-Tropan-3a-yl (-)-tropate;Cystospaz;Daturine;Duboisine;Hyoscyamine;L-Hyoscyamin;l-Atropine;
EINECS(EC#)202-933-0
Molecular FormulaC17H23NO3
Molecular Weight289.37
AppearanceWhite crystalline powder
refractive index1.581
storage temp2-8°C
Hazard T+: Very toxic;
Risk R26/28
Safety
A deadly human poison by an unspecified route. An experimental poison by intravenous route. This is one of the atropine alkaloids and is very toxic, acting very much like atropine. It has the same effect on the central nervous system but twice the effect on the peripheral nerves. The symptoms of poisoning are dryness of the throat and mouth, marked difficulty in swallowing, and a sensation of burning and thirst. The vision becomes impaired through dilation and loss of accommodation, and the eyes present a rather prominent, brilliant, staring appearance. The voice is husky and the tongue is red. When heated to decomposition it emits highly toxic fumes of NOx.
Hazard Codes:
T+: Very toxic .gif)
Risk Statements about (-)-Hyoscyamine (101-31-5):
R26/28: Very toxic by inhalation and if swallowed.
Safety Statements about (-)-Hyoscyamine (101-31-5):
S24 Avoid contact with skin.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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unr-man LDLo:1471 µg/kg
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85DCAI Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73. |
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ivn-mus LD50:95 mg/kg
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BJPCAL British Journal of Pharmacology and Chemotherapy. 24 (1965),138. |
