4,4'-Methylenedianiline cas no:101-77-9

Name4,4'-Methylenedianiline
CAS101-77-9
Synonyms4,4'-methylenedianiline; ,4'-Methylenebisaniline; 4-(4-Aminobenzyl)phenylamine; 4,4'-diaminodiphenylmethan; 4,4’-diaminoditan; 4,4'-methylenebisaniline; 4,4'-methylenebis-benzenamin; 4,4'-methylenebisbenzenamine; 4,4'-Diamino diphenyl methane; DADPM; MDA
EINECS(EC#)202-974-4
Molecular FormulaC13H14N2
Molecular Weight198.27

Appearancewhite to yellow or beige flakes or crystals
storage tempStore in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Hazardclass6.1

Hazard T:Toxic;N:Dangerousfortheenvironment;
Risk R39/23/24/25;R43;R45;R48/20/21/22;R51/53
Safety

Confirmed carcinogen with experimental tumorigenic data. Human poison by ingestion. Poison by subcutaneous and intraperitoneal routes. Human systemic effects by ingestion: rigidity, jaundice, other liver changes. An eye irritant. Mutation data reported. It is not rapidly absorbed through the skin. Combustible when exposed to heat or flame. When heated to decomposition it emits highly toxic fumes of aniline and NO_x.
Hazard Codes: T,N
Risk Statements: 45-39/23/24/25-43-48/20/21/22-51/53-68 
R45:May cause cancer. 
R39:Danger of very serious irreversible effects. 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R48:Danger of serious damage to health by prolonged exposure. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R68:Possible risk of irreversible effects.
Safety Statements: 53-45-61 
S53:Avoid exposure - obtain special instructions before use. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 2651 6.1/PG 3
WGK Germany: 3
RTECS: BY5425000
HazardClass: 6.1
PackingGroup: III

1.		eye-rbt 100 mg/24H MOD		85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,481.
2.		mmo-sat 250 μg/plate		MUREAV    Mutation Research. 67 (1979),123.
3.		mma-sat 50 μg/plate		MUREAV    Mutation Research. 67 (1979),123.
4.		dnd-rat-ipr 370 μmol/kg		CRNGDP    Carcinogenesis. 2 (1981),1317.
5.		sce-mus-ipr 9 mg/kg		MUREAV    Mutation Research. 108 (1983),225.
6.		orl-man TDLo:8420 μg/kg:CNS,LIV		BMJOAE    British Medical Journal. 1 (1966),514.
7.		orl-man TDLo:8420 μg/kg		BMJOAE    British Medical Journal. 1 (1966),514.
8.		orl-rat LD50:347 mg/kg		28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,71.
9.		ipr-rat LD50:193 mg/kg		ZHYGAM    Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. 20 (1974),393.
10.		scu-rat LD50:200 mg/kg		NATWAY    Naturwissenschaften.