4,4'-oxybisbenzenamine cas no:101-80-4
Synonyms: 4,4'-diaminodiphenyl ether; 4,4'-diaminodiphenyloxide; 4,4'-diaminophenyl ether; 4,4'-diaminophenyl oxide; 4,4-dadpe; 4,4'-Oxydianiline; 4,4'-oxydiphenylamine; 4-Aminophenyl ether; bis (p-Aminophenyl) Ether; DADPE; ODA; oxybis(4-aminobenzene); oxydi-p-phenylenediamine; oxydianiline; 4,4-Diamino diphenyl ether; 4,4'-Diamino Diphenyl Ether;
Name4,4'-oxybisbenzenamine
CAS101-80-4
Synonyms4,4'-diaminodiphenyl ether; 4,4'-diaminodiphenyloxide; 4,4'-diaminophenyl ether; 4,4'-diaminophenyl oxide; 4,4-dadpe; 4,4'-Oxydianiline; 4,4'-oxydiphenylamine; 4-Aminophenyl ether; bis (p-Aminophenyl) Ether; DADPE; ODA; oxybis(4-aminobenzene); oxydi-p-phenylenediamine; oxydianiline; 4,4-Diamino diphenyl ether; 4,4'-Diamino Diphenyl Ether;
EINECS(EC#)202-977-0
Molecular FormulaC12H12N2O
Molecular Weight200.24
Appearanceodorless colorless crystals or an odorless fine, beige powder
storage tempStorage location should be close to laboratory where it is to be used, so that only small amounts need to be transported. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Hazard T:Toxic
Risk R45;R46;R62;R23/24/25;R51/53
Safety
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:?
T,?
N
Risk Statements: 45-46-23/24/25-51/53-62-36/37/38-22?
R45:May cause cancer.?
R46:May cause heritable genetic damage.?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R62:Risk of impaired fertility.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R22:Harmful if swallowed.
Safety Statements: 53-45-61-36/37-26-20?
S53:Avoid exposure - obtain special instructions before use.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.?
S36/37:Wear suitable protective clothing and gloves.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S20:When using, do not eat or drink.
RIDADR: UN 3077 9/PG 3
WGK Germany: 3
RTECS: BY7900000
HazardClass: 6.1
PackingGroup: III
HS Code: 29222900
HS Code 29222900
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| guinea pig |
LD50 |
oral |
650mg/kg (650mg/kg) |
? |
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 43, 1982. |
| mouse |
LD50 |
intraperitoneal |
300mg/kg (300mg/kg) |
BEHAVIORAL: MUSCLE WEAKNESS
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968. |
| mouse |
LD50 |
oral |
685mg/kg (685mg/kg) |
? |
Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968. |
| rabbit |
LD50 |
intraperitoneal |
650mg/kg (650mg/kg) |
BEHAVIORAL: MUSCLE WEAKNESS
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968. |
| rabbit |
LD50 |
oral |
700mg/kg (700mg/kg) |
? |
Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968. |
| rat |
LD50 |
intraperitoneal |
365mg/kg (365mg/kg) |
BEHAVIORAL: MUSCLE WEAKNESS
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968. |
| rat |
LD50 |
oral |
725mg/kg (725mg/kg) |
? |
Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968. |
