101477-54-7|Lomerizine dihydrochlorideProducts Supply

Lomerizine dihydrochloride cas no:101477-54-7

Synonyms: Piperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-,dihydrochloride (9CI);1-(2,3,4-Trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine dihydrochloride;1-(Bis(4-fluorophenyl)methyl)-4-((2,3,4-trimethoxyphenyl)methyl)piperazine dihydrochloride;Lomerizinehydrochloride;Lomerizine HCl;

Identification

NameLomerizine dihydrochloride
CAS101477-54-7
SynonymsPiperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-,dihydrochloride (9CI);1-(2,3,4-Trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine dihydrochloride;1-(Bis(4-fluorophenyl)methyl)-4-((2,3,4-trimethoxyphenyl)methyl)piperazine dihydrochloride;Lomerizinehydrochloride;Lomerizine HCl;
Molecular FormulaC₂₇H₃₂Cl₂F₂N₂O₃
Molecular Weight541.46

Chemical Properties

Appearancecolourless crystalline solid

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	706mg/kg (706mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
mouse	LD50	intravenous	44mg/kg (44mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
mouse	LD50	oral	300mg/kg (300mg/kg)		European Patent Application. Vol. #159566,
mouse	LD50	subcutaneous	> 1200mg/kg (1200mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
rat	LD50	intravenous	27mg/kg (27mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
rat	LD50	oral	307mg/kg (307mg/kg)		Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
rat	LD50	subcutaneous	882mg/kg (882mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.

supplier list

Wuhan Pharma Chemical Co., Ltd.: Tel:+86-27-87711369; Address: 430071

Yancheng Luye Chemical Co.,Ltd.: Tel:+0086-(515)-88706161; Address: Longgang Chemical Zone, Yancheng, Jiangsu Province 224011,

Beijing Nordhuns Chemical Technology Co., Ltd.: Tel:+86-(10)-84929330, 86972915; Address: 202 Xinhengji Office Building, No.66 Beiyuan Road, Chaoyang, beijing,

Shanghai Fortune Bio-Technology Co., Ltd.: Tel:+86-(21)-6112-1584; Address: Hu Min Rd.,Minhang District, Shanghai,

Shandong Zhongke Taidou Chemical Co., Ltd.: Tel:+86-(531)-8868-2301; Address: Hongyuan Development Park, Jinan, Shandong 250100,

Ji'nan Zhongke Yitong Chemical Co.,Ltd.: Tel:+86-(531)-8865-8009; Address: No.106 Industry South Road, Jinan, Shandong 250100,

Beijing Huikang Boyuan Chemical Tech Co.,LTD: Tel:+86-10-68862197，68867502; Address: No.7 Haiying Road,Science City,Fengtai District,Beijing,China

Beijing Team Academy of Pharmaceutical Sciences Co., Ltd: Tel:86-10-68180921 , 13501010127,13911611675; Address: No. 329,Jiangjiafen Road, Fengtai District, Beijing, P.R.China

ZHONGBEI NORTHLAND BIO-CHEM INDUSTRY CO., LTD.: Tel:+86-452-6197139; Address: SONGLING DISTRICT, JIAGEDAQI CITY, DAXINGANLING, HEILONGJIANG PROVINCE, CHINA

Suzhou Toprun Imp. & Exp. Trading Co., Ltd.: Tel:0086-512-67541576 15862383109; Address: Rm.405,No.1718,Ren Min Road,Suzhou,215005 ,P.R. China

Yancheng Foyo Pharm. & Chem. Co., Ltd: Tel:+86-519-86315721; Address: Touzeng, Binhai, Yancheng, Jiangsu, China

Yancheng Lvye Chemical Co., Ltd.: Tel:0086-515-88710661; Address: No.62, kalfang Avenue, Yancheng Jiangsu, CHINA

Taizhou Ingore Bio & Tech Co., Ltd: Tel:+86-571-86044171; Address: Huatao ,Tiantai County,Zhejiang,China

AOPHARM: Tel:86-311-66600578; Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.

Jinan Haohua Industry Co., Ltd.: Tel:0086-531-58773055; Address: No.59 Gongye South RD

Lomerizine dihydrochloride cas no:101477-54-7

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