101477-54-7|Lomerizine dihydrochlorideProducts Supply

Lomerizine dihydrochloride cas no:101477-54-7

Synonyms: Piperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-,dihydrochloride (9CI);1-(2,3,4-Trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine dihydrochloride;1-(Bis(4-fluorophenyl)methyl)-4-((2,3,4-trimethoxyphenyl)methyl)piperazine dihydrochloride;Lomerizinehydrochloride;Lomerizine HCl;

Identification

NameLomerizine dihydrochloride
CAS101477-54-7
SynonymsPiperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-,dihydrochloride (9CI);1-(2,3,4-Trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine dihydrochloride;1-(Bis(4-fluorophenyl)methyl)-4-((2,3,4-trimethoxyphenyl)methyl)piperazine dihydrochloride;Lomerizinehydrochloride;Lomerizine HCl;
Molecular FormulaC₂₇H₃₂Cl₂F₂N₂O₃
Molecular Weight541.46

Chemical Properties

Appearancecolourless crystalline solid

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	706mg/kg (706mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
mouse	LD50	intravenous	44mg/kg (44mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
mouse	LD50	oral	300mg/kg (300mg/kg)		European Patent Application. Vol. #159566,
mouse	LD50	subcutaneous	> 1200mg/kg (1200mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
rat	LD50	intravenous	27mg/kg (27mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
rat	LD50	oral	307mg/kg (307mg/kg)		Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.
rat	LD50	subcutaneous	882mg/kg (882mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Cardiovascular Drug Reviews. Vol. 8, Pg. 105, 1990.

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Suzhou Kaiyuan Minsheng Chemicals Technology Co., Ltd.: Tel:+86-(512)-62887188; Address: No.68 Qunxing, No.2 Road, Suzhou Industrial Park, Suzhou 215006,

Wuhan Pharma Chemical Co., Ltd.: Tel:+86-27-87711369; Address: 430071

Taizhou Ingore Bio & Tech Co., Ltd.: Tel:+86-(571)-86044071; Address: Huatao, Tiantai County, Taizhou, Zhejiang 317207,

Taizhou Crene Chempharm Co., Ltd.: Tel:+86-(576)-88813233; Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000,

ZHONGBEI NORTHLAND BIO-CHEM INDUSTRY CO., LTD.: Tel:+86-452-6197139; Address: SONGLING DISTRICT, JIAGEDAQI CITY, DAXINGANLING, HEILONGJIANG PROVINCE, CHINA

HangZhou Peak Chemical Co.,Ltd: Tel:+86-571-88233073; Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China

Shandong Jinan Wedo Chemical Co.,Ltd: Tel:+86-531-55503859; Address: No.36, Gongyenan Road.,Jinan, Shandong,China.

shandong zhongke taidou chemical co.,ltd: Tel:86-531-88682301; Address: Jinan shandong Province CHina

Yancheng Foyo Pharm. & Chem. Co., Ltd: Tel:+86-519-86315721; Address: Touzeng, Binhai, Yancheng, Jiangsu, China

AOPHARM: Tel:86-311-66600578; Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.

Jinan Haohua Industry Co., Ltd.: Tel:0086-531-58773055; Address: No.59 Gongye South RD

Shanghai UCHEM Inc.: Tel:086-021-31615209; Address: 8 Liuying Rd, Hongkou, Shanghai

Wuhan Fortuna Chemical Co., Ltd.: Tel:0086-27-59207850; Address: A2705,Dong Yi Shi Qu,129# XinHua Road

Hangzhou J&H Chemical Co., Ltd: Tel:86-571-87396430; Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Lomerizine dihydrochloride cas no:101477-54-7

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