101530-10-3|1H-Imidazole-1-acetonitrile,a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (aE)-Products Supply

1H-Imidazole-1-acetonitrile,a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (aE)- cas no:101530-10-3

Synonyms: NND 318;TJN 318;1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (E)-;Astat;Latoconazole;

Identification

Name1H-Imidazole-1-acetonitrile,a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (aE)-
CAS101530-10-3
SynonymsNND 318;TJN 318;1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (E)-;Astat;Latoconazole;
EINECS(EC#)203-865-4
Molecular FormulaC₁₄H₁₀ClN₃S₂
Molecular Weight319.84

Chemical Properties

AppearanceLight-Yellow Crystals
refractive index1.725
storage temp2-8°C

Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Safety Information of Lanoconazole (101530-10-3):
Hazard Codes: Xn
Risk Statements: 22
22: Harmful if swallowed
RTECS: NI3393500

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	subcutaneous	2gm/kg (2000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: OTHER CHANGES BLOOD: NORMOCYTIC ANEMIA	Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 137, 1992.
mouse	LD	subcutaneous	> 5gm/kg (5000mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 195, 1992.
mouse	LD50	intraperitoneal	1743mg/kg (1743mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 195, 1992.
mouse	LD50	oral	2715mg/kg (2715mg/kg)	AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 195, 1992.
rat	LD	skin	> 5gm/kg (5000mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 195, 1992.
rat	LD	subcutaneous	> 5gm/kg (5000mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 195, 1992.
rat	LD50	intraperitoneal	1655mg/kg (1655mg/kg)	AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: REGIDITY	Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 195, 1992.
rat	LD50	oral	652mg/kg (652mg/kg)	AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 195, 1992.

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1H-Imidazole-1-acetonitrile,a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (aE)- cas no:101530-10-3

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