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Thiosulfuric acid(H2S2O3), gold(1+) sodium salt (2:1:3), dihydrate (9CI) cas no:10210-36-3

Synonyms: Gold sodiumthiosulfate dihydrate; Sodium aurotiosulfate; Thiochrysine

Identification
NameThiosulfuric acid(H2S2O3), gold(1+) sodium salt (2:1:3), dihydrate (9CI)
CAS10210-36-3
SynonymsGold sodiumthiosulfate dihydrate; Sodium aurotiosulfate; Thiochrysine
EINECS(EC#)233-563-8
Molecular FormulaAu. 2 H2 O3 S2 . 2 H2 O . 3 Na
Molecular Weight526.22
Safety Data

Safety

Poison by subcutaneous, intraperitoneal, intravenous, and intramuscular routes. Human systemic effects by intramuscular route: dermatitis, granulocytopenia, and thrombocytopenia. Used as an antirheumatic agent. When heated to decomposition it emits very toxic fumes of SOx and Na2O.
Hazard Codes: IrritantXi
Risk Statements: 36/37/38 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.


Toxicity
1.    

ims-hmn TDLo:400 µg/kg/1W:SKN,BLD

    AIMEAS    Annals of Internal Medicine. 37 (1952),323.
2.    

scu-rat LDLo:30 mg/kg

    27ZWAY    Heffters Handbuch der Experimentelle Pharmakologie. 3.3,2134,- .
3.    

ivn-rat LDLo:80 mg/kg

    27ZWAY    Heffters Handbuch der Experimentelle Pharmakologie. 3.3,2134,- .
4.    

ims-rat LDLo:35 mg/kg

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 49 (1942),121.
5.    

ipr-mus LD50:110 mg/kg

    JRHUA9    Journal of Rheumatology. 12 (1985),274.
6.    

ivn-mus LDLo:100 mg/kg

    EMSUA8    Experimental Medicine and Surgery. 3 (1945),146.
7.    

ivn-rbt LDLo: 59 mg/kg

    27ZWAY    Heffters Handbuch der Experimentelle Pharmakologie. 3.3,2134,- .
8.    

scu-gpg LDLo:60 mg/kg

    ZGEMAZ    Zeitschrift fuer die Gesamte Experimentelle Medizin. 57 (1927),77.

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