Acetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, hydrochloride (1:1) cas no:1027-14-1
Synonyms: Acetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, monohydrochloride (9CI);Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-, monohydrochloride (8CI);Acetanilide, 2-diethylamino-2',4',6'-trimethyl-, hydrochloride (6CI); Mesocain;Mesocaine; Trimecaine hydrochloride; Trimekain hydrochloride
NameAcetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, hydrochloride (1:1)
CAS1027-14-1
SynonymsAcetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, monohydrochloride (9CI);Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-, monohydrochloride (8CI);Acetanilide, 2-diethylamino-2',4',6'-trimethyl-, hydrochloride (6CI); Mesocain;Mesocaine; Trimecaine hydrochloride; Trimekain hydrochloride
EINECS(EC#)213-836-8
Molecular FormulaC15H24 N2 O . Cl H
Molecular Weight284.87
Safety
Poison by intraperitoneal and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
172mg/kg (172mg/kg) |
|
Acta Facultatis Pharmaceuticae, Universitatis Comenianae. Vol. 29, Pg. 81, 1976. |
| mouse |
LD50 |
intravenous |
50mg/kg (50mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Farmakologiya i Toksikologiya Vol. 25, Pg. 731, 1962. |
| mouse |
LD50 |
subcutaneous |
295mg/kg (295mg/kg) |
|
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 1526, 1989. |
| rabbit |
LD50 |
intraperitoneal |
95mg/kg (95mg/kg) |
|
Drug Metabolism and Drug Interactions. Vol. 9, Pg. 321, 1991.
|
