N-(2-Hydroxyethyl)piperazine cas no:103-76-4

NameN-(2-Hydroxyethyl)piperazine
CAS103-76-4
Synonyms1-Piperazineethanol; 1-(2-Hydroxyethyl)piperazine; 2-piperazin-1-ylethanol; 2-(1-Piperazino)ethanol; Hydroxyethyl piperazine; N-(2-Hydroxyethyl) piperazine
EINECS(EC#)203-142-3
Molecular FormulaC6H14N2O
Molecular Weight130.19

Appearanceclear to pale yellow liquid
refractive index1.5055-1.5075
storage tempKeep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Hazard Xi:Irritant
Risk R38;R41
Safety Hazard Codes:Xi
Risk Statements:36/37/38-41-38
36/37/38:Irritating to eyes, respiratory system and skin
41:Risk of serious damage to eyes
38:Irritating to the skin
Safety Statements:26-36/39-37/39
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/39:Wear suitable protective clothing and eye/face protection
37/39:Wear suitable protective clothing, gloves and eye/face protection
WGK Germany:1
Hazard Note:Irritant
HS Code:29335995

HS Code 29335995

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TL6825000

CHEMICAL NAME :

1-Piperazineethanol

CAS REGISTRY NUMBER :

103-76-4

BEILSTEIN REFERENCE NO. :

0104361

LAST UPDATED :

199710

DATA ITEMS CITED :

9

MOLECULAR FORMULA :

C6-H14-N2-O

MOLECULAR WEIGHT :

130.22

WISWESSER LINE NOTATION :

T6M DNTJ D2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Open irritation test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/6/1970

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,865,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

4920 uL/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

3350 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - muscle contraction or spasticity

REFERENCE :

GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(5),67,1980

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

>5 mL/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/6/1970

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

3720 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - muscle contraction or spasticity

REFERENCE :

GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(5),67,1980