103-85-5|Thiourea, N-phenyl-Products Supply - Chemical intermediates Network

Thiourea, N-phenyl- cas no:103-85-5

Synonyms: Thiourea,phenyl- (9CI);Urea, 1-phenyl-2-thio- (8CI);1-Phenyl-2-thiourea;1-Phenylthiourea;N-Phenylthiourea;NSC 5779;PTU;Phenylthiocarbamide;Phenylthiourea;U 6324;a-Phenylthiourea;

Identification

NameThiourea, N-phenyl-
CAS103-85-5
SynonymsThiourea,phenyl- (9CI);Urea, 1-phenyl-2-thio- (8CI);1-Phenyl-2-thiourea;1-Phenylthiourea;N-Phenylthiourea;NSC 5779;PTU;Phenylthiocarbamide;Phenylthiourea;U 6324;a-Phenylthiourea;
EINECS(EC#)203-151-2
Molecular FormulaC₇H₈N₂S
Molecular Weight152.21

Chemical Properties

AppearanceSlightly yellow powder
refractive index1.725
storage tempPoison room

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1

Safety Data

Hazard T+
Risk R28
Safety

Dangerous disaster hazard; emits toxic fumes of oxides of sulfur and nitrogen when heated to decomposition. Avoid acids or acid fumes.
Safety Information of 1-Phenyl-2-thiourea (103-85-5):
Hazard Codes: T+
Risk Statements: 28-43
28: Very Toxic if swallowed
43: May cause sensitization by skin contact
Safety Statements: 28-36/37-45
28: After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36: Wear suitable protective clothing
37: Wear suitable gloves
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Toxicity

1-Phenyl-2-thiourea (103-85-5) is classified as extremely toxic. The probable oral lethal dose is 5-50 mg/kg or between 7 drops and 1 teaspoon for a 70 kg (150 lb.) person.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	25mg/kg (25mg/kg)		National Technical Information Service. Vol. AD277-689,
mouse	LD50	oral	10mg/kg (10mg/kg)		Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973,
rabbit	LD50	oral	40mg/kg (40mg/kg)		Journal of Medicinal and Pharmaceutical Chemistry. Vol. 4, Pg. 109, 1961.
rat	LD50	intraperitoneal	5mg/kg (5mg/kg)	ENDOCRINE: HYPERGLYCEMIA	Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 186, 1947.
rat	LD50	oral	3mg/kg (3mg/kg)		Journal of Medicinal and Pharmaceutical Chemistry. Vol. 4, Pg. 109, 1961.

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Thiourea, N-phenyl- cas no:103-85-5

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