1H-Isoindole-1,3(2H)-dione,2-[7-fluoro-3,4-dihydro-3-oxo-4-(2-propyn-1-yl)-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro- cas no:103361-09-7

Name1H-Isoindole-1,3(2H)-dione,2-[7-fluoro-3,4-dihydro-3-oxo-4-(2-propyn-1-yl)-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-
CAS103361-09-7
Synonyms1H-Isoindole-1,3(2H)-dione,2-[7-fluoro-3,4-dihydro-3-oxo-4-(2-propynyl)-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-(9CI);2-(7-Fluoro-3-oxo-4-(properties-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4,5,6,7-tetrahydro-2H-isoindole-1,3-dione;7-Fluoro-6-(3,4,5,6-tetrahydrophthalimido)-4-(2-propynyl)-1,4-benzoxazin-3(2H)-one;Flumizin;
Molecular FormulaC₁₉H₁₅FN₂O₄
Molecular Weight354.336

refractive index1.661
storage temp0-6°C

Hazard T: Toxic;N: Dangerous for the environment;
Risk R61
Safety

Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NO_x and F⁻.
 

Hazard Codes: T,N
Risk Statements:
50:  Very Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
61:  May cause harm to the unborn child 
Safety Statements:
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53:  Avoid exposure - obtain special instruction before use
60:  This material and/or its container must be disposed of as hazardous waste
61:  Avoid release to the environment. Refer to special instructions safety data sheet

CHEMICAL IDENTIFICATION

RTECS NUMBER :

NR3399382

CHEMICAL NAME :

1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-(7-fluoro-3,4-dihydro-3-oxo-4- (2-propynyl)-2H-1,4-benzoxazin-6-yl)-

CAS REGISTRY NUMBER :

103361-09-7

LAST UPDATED :

199712

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C19-H15-F-N2-O4

MOLECULAR WEIGHT :

354.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

300 mg/kg

SEX/DURATION :

female 6-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system

REFERENCE :

CGANE7 Congenital Anomalies. (Nippon Senten Ijo Gakkai, 377-2 Ono-higashi, Osakasayama, Osaka-Fu 589 Japan) V.27- 1987- Volume(issue)/page/year: 35,123,1995

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

1 gm/kg

SEX/DURATION :

female 12 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow)

REFERENCE :

TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 54,237,1996