10347-81-6|9,10-Ethanoanthracene-9(10H)-propanamine,N-methyl-, hydrochloride (1:1)Products Supply

9,10-Ethanoanthracene-9(10H)-propanamine,N-methyl-, hydrochloride (1:1) cas no:10347-81-6

Synonyms: 9,10-Ethanoanthracene-9(10H)-propanamine,N-methyl-, hydrochloride (9CI);9,10-Ethanoanthracene-9(10H)-propylamine,N-methyl-, hydrochloride (7CI,8CI);9,10-Dihydro-9-(3-methylaminopropyl)-9,10-ethanoanthracene hydrochloride;9-[g-(Methylamino)propyl]-9,10-dihydro-9,10-ethanoanthracenehydrochloride;CIBA 34,276Ba;CIBA 34276 hydrochloride;Ladiomil;Ludiomil;Psymion;

Identification

Name9,10-Ethanoanthracene-9(10H)-propanamine,N-methyl-, hydrochloride (1:1)
CAS10347-81-6
Synonyms9,10-Ethanoanthracene-9(10H)-propanamine,N-methyl-, hydrochloride (9CI);9,10-Ethanoanthracene-9(10H)-propylamine,N-methyl-, hydrochloride (7CI,8CI);9,10-Dihydro-9-(3-methylaminopropyl)-9,10-ethanoanthracene hydrochloride;9-[g-(Methylamino)propyl]-9,10-dihydro-9,10-ethanoanthracenehydrochloride;CIBA 34,276Ba;CIBA 34276 hydrochloride;Ladiomil;Ludiomil;Psymion;
EINECS(EC#)233-758-8
Molecular FormulaC₂₀H₂₃N^.HCl
Molecular Weight277.40332

Chemical Properties

Appearancewhite powder

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard Xn:Harmful;
Risk R22
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects: arrhythmias, coma, convulsions, distorted perceptions, general anesthesia, hallucinations, pulse rate increase, respiration changes. An experimental teratogen. Experimental reproductive effects. An antidepressant. When heated to decomposition it emits toxic fumes of NO_x and HCl.
Hazard Codes Harmful Xn
Risk Statements 22
R22:Harmful if swallowed.
RIDADR 3249
WGK Germany 3
RTECS KJ4555000
HazardClass 6.1(b)
PackingGroup III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	intravenous	30mg/kg (30mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Bollettino Chimico Farmaceutico. Vol. 112, Pg. 601, 1973.
cat	LDLo	oral	> 300mg/kg (300mg/kg)		Bollettino Chimico Farmaceutico. Vol. 112, Pg. 601, 1973.
child	TDLo	oral	12mg/kg (12mg/kg)	CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	American Journal of Emergency Medicine. Vol. 6, Pg. 247, 1988.
dog	LDLo	intravenous	20mg/kg (20mg/kg)		Bollettino Chimico Farmaceutico. Vol. 112, Pg. 782, 1973.
dog	LDLo	oral	20mg/kg (20mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Bollettino Chimico Farmaceutico. Vol. 112, Pg. 601, 1973.
human	TDLo	oral	17mg/kg (17mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	British Medical Journal. Vol. 1, Pg. 1573, 1977.
man	TDLo	oral	490ug/kg (0.49mg/kg)	BEHAVIORAL: SLEEP	Journal of Clinical Psychiatry. Vol. 47, Pg. 210, 1986.
man	TDLo	oral	391mg/kg/1Y-I (391mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD KIDNEY, URETER, AND BLADDER: INCONTINENCE	Postgraduate Medical Journal. Vol. 55, Pg. 742, 1979.
mouse	LD50	intraperitoneal	125mg/kg (125mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 229, Pg. 163, 1977.
mouse	LD50	intravenous	31mg/kg (31mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Bollettino Chimico Farmaceutico. Vol. 112, Pg. 601, 1973.
mouse	LD50	oral	480mg/kg (480mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 1, Pg. 207, 1975.
mouse	LD50	subcutaneous	310mg/kg (310mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 1, Pg. 207, 1975.
rabbit	LDLo	intravenous	20mg/kg (20mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Bollettino Chimico Farmaceutico. Vol. 112, Pg. 601, 1973.
rabbit	LDLo	oral	> 1gm/kg (1000mg/kg)		Bollettino Chimico Farmaceutico. Vol. 112, Pg. 601, 1973.
rat	LD50	intraperitoneal	72mg/kg (72mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Bollettino Chimico Farmaceutico. Vol. 112, Pg. 601, 1973.
rat	LD50	intravenous	35mg/kg (35mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 1, Pg. 207, 1975.
rat	LD50	oral	760mg/kg (760mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Bollettino Chimico Farmaceutico. Vol. 112, Pg. 601, 1973.
rat	LD50	subcutaneous	170mg/kg (170mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Bollettino Chimico Farmaceutico. Vol. 112, Pg. 601, 1973.
women	LDLo	oral	90mg/kg (90mg/kg)	BEHAVIORAL: COMA	Journal of Analytical Toxicology. Vol. 6, Pg. 199, 1982.
women	TDLo	oral	7mg/kg/1W-I (7mg/kg)	BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Journal of Clinical Pyschopharmacology. Vol. 3, Pg. 264, 1983.
women	TDLo	oral	20mg/kg (20mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP	American Journal of Emergency Medicine. Vol. 2, Pg. 144, 1984.
women	TDLo	oral	63mg/kg/6W-I (63mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD KIDNEY, URETER, AND BLADDER: INCONTINENCE	Postgraduate Medical Journal. Vol. 55, Pg. 742, 1979.
women	TDLo	oral	75mg/kg (75mg/kg)	BEHAVIORAL: COMA CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP	Intensive Care Medicine. Vol. 11, Pg. 220, 1985.

supplier list

INFA S.P.A.: Tel:+39-02-777281; Address: Via Salvini 10, 20122 Milan (Italy)

Beijing Merson pharmaceutical Co., Ltd.: Tel:; Address: 2nd Floor, No.2 Building, No.14 Houshayu Duan, Jingmi Road ,Shunyi District ,Beijing 101318, P.R.China

Credimate Trading Limited: Tel:+86-(21)-57429129; Address: Suite 302, No. 503 Guhuaxincun Area B, Nanqiao, Fengxian, Shanghai 201400,

ACIC Fine Chemicals Inc.: Tel:+1-(800)-265-6727; Address: 11772 West Sample Road, Coral Springs, Florida 33065,

AFINE CHEMICALS LIMITED: Tel:86-571-85232161; Address: 6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road Shirley, NY 11967, USA

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Wuhan Fortuna Chemical Co., Ltd.: Tel:0086-27-59207850; Address: A2705,Dong Yi Shi Qu,129# XinHua Road

Andexin industrial Co.,Limited: Tel:86-411-39074598; Address: No.98,Shengli road,,Jinzhou district,

AOPHARM: Tel:86-311-66600578; Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.

HANGZHOU HOLYPHARM BIOTECH CO.,LTD: Tel:86 571 87176852; Address: Room 802,Block C EAC,NO.18,JiaogongRoad

wuhan cillin chemical: Tel:+86-15527136576; Address: Wuhan city

wdfpharma: Tel:+86 576 8829 0708; Address: 402,28 Yanyu Road,Jiaojiang,Taizhou 318000,Zhejiang,China

Zhejiang Wonderful Pharma & Chem Co.: Tel:; Address:

Beijing Merson Pharmaceutical Technology Development Co., Ltd.: Tel:+86-(10)-80484574, 8048344; Address: 2nd Floor , No. 2 Building , No. 14 Houshayu Duan, Jingmi Road, Shunyi, Beijing 101318,

9,10-Ethanoanthracene-9(10H)-propanamine,N-methyl-, hydrochloride (1:1) cas no:10347-81-6

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