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Benzenemethanol, a-(aminomethyl)-4-hydroxy- cas no:104-14-3

Synonyms: Benzylalcohol, a-(aminomethyl)-p-hydroxy-(6CI,8CI); (RS)-Octopamine; (?à)-Octopamine; 1-(p-Hydroxyphenyl)-2-aminoethanol;2-Amino-1-(4-hydroxyphenyl)ethanol; 4-Hydroxyphenethanolamine;4-[2-Amino-1-hydroxyethyl]phenol; Analet; DL-Octopamine; ND 50; Norden;Norphen; Norsympathol; Norsympatol; Norsynephrine; Norton; Octopamine; Racemicoctopamine; Win 5512; dl-Octopamine; p-Hydroxyphenylethanolamine; p-Octopamine;a-(Aminomethyl)-p-hydroxybenzylalcohol; b-Hydroxy-b-(4-hydroxyphenyl)ethylamine

Identification
NameBenzenemethanol, a-(aminomethyl)-4-hydroxy-
CAS104-14-3
SynonymsBenzylalcohol, a-(aminomethyl)-p-hydroxy-(6CI,8CI); (RS)-Octopamine; (?à)-Octopamine; 1-(p-Hydroxyphenyl)-2-aminoethanol;2-Amino-1-(4-hydroxyphenyl)ethanol; 4-Hydroxyphenethanolamine;4-[2-Amino-1-hydroxyethyl]phenol; Analet; DL-Octopamine; ND 50; Norden;Norphen; Norsympathol; Norsympatol; Norsynephrine; Norton; Octopamine; Racemicoctopamine; Win 5512; dl-Octopamine; p-Hydroxyphenylethanolamine; p-Octopamine;a-(Aminomethyl)-p-hydroxybenzylalcohol; b-Hydroxy-b-(4-hydroxyphenyl)ethylamine
EINECS(EC#)203-179-5
Molecular FormulaC8H11 N O2
Molecular Weight153.20
Chemical Properties
AppearanceWhite to off-white powder
refractive index1.614
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Safety

Poison by intravenous route. Moderately toxic by intraperitoneal and subcutaneous route. When heated to decomposition it emits toxic fumes of NOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intravenous 200mg/kg (200mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 101, Pg. 81, 1955.
mouse LD50 intracrebral 2100mg/kg (2100mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64(4), Pg. 140S, 1968.
mouse LD50 intraperitoneal 600mg/kg (600mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 106, Pg. 341, 1952.
mouse LD50 intravenous 75mg/kg (75mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 106, Pg. 341, 1952.
mouse LD50 oral 4200mg/kg (4200mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64(4), Pg. 140S, 1968.
mouse LD50 subcutaneous 2070mg/kg (2070mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64(4), Pg. 140S, 1968.
rat LD50 intraperitoneal 1350mg/kg (1350mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64(4), Pg. 140S, 1968.
rat LD50 oral 1240mg/kg (1240mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64(4), Pg. 140S, 1968.
rat LD50 subcutaneous 350mg/kg (350mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64(4), Pg. 140S, 1968.

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Zhejiang Longyou Best Additive Co., Ltd.
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Shanghai Fuhe chemistry Technology Co.Ltd.
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Pure Synmr Ingredients Limited
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