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p-Anisidine cas no:104-94-9

Synonyms: 4-Aminoanisole; 4-Methoxyaniline; 4-Methoxybenzeneamine; Para-Anisidine; P-Aminoanisole

Identification
Namep-Anisidine
CAS104-94-9
Synonyms4-Aminoanisole; 4-Methoxyaniline; 4-Methoxybenzeneamine; Para-Anisidine; P-Aminoanisole
EINECS(EC#)203-254-2
Molecular FormulaC7H9NO
Molecular Weight123.15
Chemical Properties
Appearancewhite, fused crystalline solid, characteristic amine odor
refractive index1.5559
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard T+:Verytoxic;N:Dangerousfortheenvironment;
Risk R26/27/28;R33;R45;R50
Safety

Hazard Codes:?VeryT+,?DangerousN,?IrritantXi
Risk Statements: 45-26/27/28-33-50?
R45:May cause cancer.?
R26/27/28:Very toxic by inhalation, in contact with skin and if swallowed.?
R33:Danger of cumulative effects.?
R50:Very toxic to aquatic organisms.
Safety Statements: 53-28-36/37-45-61
S53:Avoid exposure - obtain special instructions before use.?
S28:After contact with skin, wash immediately with plenty of soap-suds.?
S36/37:Wear suitable protective clothing and gloves.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.??
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 2
RTECS: BZ5450000
F: 8
HazardClass: 6.1
PackingGroup: III
HS Code: 29222200


HS Code 29222200

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 806mg/kg (806mg/kg) ? Journal of Medicinal Chemistry. Vol. 17, Pg. 900, 1974.
mouse LD50 oral 1410mg/kg (1410mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: ATAXIA
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 184, 1992.
rabbit LD50 oral 2900mg/kg (2900mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES

BLOOD: OTHER CHANGES

BLOOD: NORMOCYTIC ANEMIA
IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 27, Pg. 63, 1982.
rat LD50 intraperitoneal 1400mg/kg (1400mg/kg) ? Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 15, Pg. 447, 1957.
rat LD50 oral 1320mg/kg (1320mg/kg) ? Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. Vol. 128, Pg. 14, 1979.
rat LD50 skin 3200mg/kg (3200mg/kg) ? Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 15, Pg. 447, 1957.

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