Trospium chloride cas no:10405-02-4
Synonyms: Spiro[1aH,5aH-nortropane-8,1'-pyrrolidinium], 3a-hydroxy-, chloride, benzilate(8CI);Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium],3-[(hydroxydiphenylacetyl)oxy]-, chloride, (1a,3b,5a)- (9CI);Benzilic acid, esterwith 3a-hydroxyspiro[1aH,5aH-nortropane-8,1'-pyrrolidinium] chloride (8CI);AsXVII;Azoniaspiro compound XVII;Azoniaspiro(3a-benziloyloxynortropane-8,1'-pyrrolidine) chloride;Keptan;Relaspium;Sanctura;Spasmex;Spasmo 3;Spasmo-lyt;
NameTrospium chloride
CAS10405-02-4
SynonymsSpiro[1aH,5aH-nortropane-8,1'-pyrrolidinium], 3a-hydroxy-, chloride, benzilate(8CI);Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium],3-[(hydroxydiphenylacetyl)oxy]-, chloride, (1a,3b,5a)- (9CI);Benzilic acid, esterwith 3a-hydroxyspiro[1aH,5aH-nortropane-8,1'-pyrrolidinium] chloride (8CI);AsXVII;Azoniaspiro compound XVII;Azoniaspiro(3a-benziloyloxynortropane-8,1'-pyrrolidine) chloride;Keptan;Relaspium;Sanctura;Spasmex;Spasmo 3;Spasmo-lyt;
EINECS(EC#)233-875-4
Molecular FormulaC25H30NO3
Molecular Weight427.97
Appearancewhite to off-white powder
Safety
Poison by subcutaneous, intravenous and intraperitoneal routes. Moderately toxic by ingestion and intraduodenal routes. When heated to decomposition it emits toxic fumes of Cl? and NOx.
| 1. |
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orl-rat LD50:1510?mg/kg
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NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),137. |
| 2. |
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ipr-rat LD50:97,700?μg/kg
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NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),137. |
| 3. |
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scu-rat LD50:707?mg/kg
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NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),137. |
| 4. |
??? |
ivn-rat LD50:15,500?μg/kg
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??? |
NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),137. |
| 5. |
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idu-rat LDLo:500?mg/kg
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ARZNAD ?? Arzneimittel-Forschung. Drug Research. 25 (1975),1037. |
| 6. |
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orl-mus LD50:812?mg/kg
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NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),137. |
| 7. |
??? |
ipr-mus LD50:50?mg/kg
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??? |
NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),137. |
| 8. |
??? |
scu-mus LD50:203?mg/kg
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??? |
NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),137. |
| 9. |
??? |
ivn
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