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Ethyl chloroacetate cas no:105-39-5

Synonyms: Ethyl chloroacetate,(Chloroacetic acid ethyl ester); Chloroacetic acid ethyl ester

Identification
NameEthyl chloroacetate
CAS105-39-5
SynonymsEthyl chloroacetate,(Chloroacetic acid ethyl ester); Chloroacetic acid ethyl ester
EINECS(EC#)203-294-0
Molecular FormulaC4H7ClO2
Molecular Weight122.55
Chemical Properties
AppearanceClear liquid
refractive index1.42-1.422
storage tempFlammables area
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard T:Toxic
Risk R10;R23/24/25;R50
Safety

Hazard Codes:?ToxicT,DangerousN
Risk Statements: 23/24/25-50-10?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.?
R50: Very toxic to aquatic organisms.?
R10: Flammable.
Safety Statements: 45-61-7/9-16?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.?
S7: Keep container tightly closed.?
S9: Keep container in a well-ventilated place.?
S16: Keep away from sources of ignition.
RIDADR: UN 1181 6.1/PG 2
WGK Germany: 2
RTECS: AF9110000
HazardClass: 6.1
PackingGroup: II
Hazardous Substances Data: 105-39-5(Hazardous Substances Data)
Poison by skin contact and subcutaneous routes. A severe eye irritant. Questionable carcinogen with experimental neoplastigenic data. Flammable liquid; a dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. Will react with water or steam to produce toxic and corrosive fumes. Vigorous reaction with sodium cyanide. To fight fire, use water, foam, CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of Cl?.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 350mg/kg (350mg/kg) ? Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 59, 1986.
mouse LD50 subcutaneous 250mg/kg (250mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954.
rabbit LD50 skin 230mg/kg (230mg/kg) ? Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977.
rat LC50 inhalation 3330uL/m3/4H (3.33mL/m3) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 71, 1993.
rat LD50 oral 180mg/kg (180mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 71, 1993.
rat LD50 skin 161mg/kg (161mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 71, 1993.

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