105628-07-7|Fasudil hydrochlorideProducts Supply - Chemical intermediates Network

Fasudil hydrochloride cas no:105628-07-7

Synonyms: Isoquinoline,5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1);1H-1,4-Diazepine,hexahydro-1-(5-isoquinolinylsulfonyl)-, monohydrochloride (9CI);1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride;Fasudilhydrochloride;

Identification

NameFasudil hydrochloride
CAS105628-07-7
SynonymsIsoquinoline,5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1);1H-1,4-Diazepine,hexahydro-1-(5-isoquinolinylsulfonyl)-, monohydrochloride (9CI);1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride;Fasudilhydrochloride;
Molecular FormulaC₁₄H₁₈ClN₃O₂S
Molecular Weight327.82962

Chemical Properties

AppearanceWhite Solid

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
monkey	LD50	intravenous	20mg/kg (20mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 740, 1995.
mouse	LD50	intravenous	67600ug/kg (67.6mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: STRAUB TAIL	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
mouse	LD50	oral	274mg/kg (274mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
mouse	LD50	subcutaneous	124mg/kg (124mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
rat	LD50	intravenous	59900ug/kg (59.9mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
rat	LD50	oral	335mg/kg (335mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
rat	LD50	subcutaneous	123mg/kg (123mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,

supplier list

ZHEJIANG XINHUA PHARMACEUTICAL CO., LTD.: Tel:+86-576-85588383; Address: Linhai Zone, Linhai, Zhejiang, China

Lotus chemical (HK) Limited: Tel:+86-(23)-86092822; Address: 602 Room, 172#, Gaoyan Road, Yubei, Chongqing 401120,

LC Laboratories: Tel:+1-(781)-937-0777; Address: 165 New Boston Street, Woburn, Massachusetts 01801,

Inter-Chemical Ltd.: Tel:+86-(755)-82187211, 82192202; Address: B-1108/1109, Tian An International Bldg., RenMin Nan Road, ShenZhen 518005,

Chengdu Sino-Strong Pharmaceutical Co., Ltd.: Tel:+86-(28)-82783659; Address: 459 West Haike Road, Cross-Straits Technological Industry Park, Wenjiang District, Chengdu 611130,

Yong Yang Pharmaceutical Co., Ltd.: Tel:+86-(531)-82373730; Address: C419, No.19 Huaneng Road, Jinan, Shandong 250100,

Shanghai Kairen Industrial Co., Ltd.: Tel:+86-(21)-64120566; Address: Room 107, No.2 dong, 3800 Chunshen Rd(Jinyan Edifice), Minhang, Shanghai 201100,

Shanghai DND Pharm-Technology Co.,Inc.: Tel:+86-(21)-58783620, 58783570; Address: No.2-18A, Lane 85, Rongcheng Road, Pudong, Shanghai 200120,

ALL PRO CORPORATION: Tel:86-532-82850205; Address: No.592, TONGHE ROAD, QINGDAO, CHINA

Beijing Lunarsun Pharmaceutical Co.,Ltd.: Tel:0086-10-81760170/71/72; Address: Anli Road, Chaoyang District,Beijing

Idea Dao Inrernational Group Co.,Limited: Tel:13720424382; Address: NO.1 cuihua road XIAN

lotuschem: Tel:852-29738324; Address: Rm. 907. JCD116 Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong

Ningbo Zhengzhang Chemical Co., Ltd: Tel:+86-21-64303067; Address: 1#Dayun Read

shandong zhongke taidou chemical co.,ltd: Tel:86-531-88682301; Address: Jinan shandong Province CHina

Yurui(Shanghai) Chemical Co.,Ltd: Tel:86-21-50456736; Address: No.188,Zhangyang Road

Fasudil hydrochloride cas no:105628-07-7

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