105628-07-7|Fasudil hydrochlorideProducts Supply - Chemical intermediates Network

Fasudil hydrochloride cas no:105628-07-7

Synonyms: Isoquinoline,5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1);1H-1,4-Diazepine,hexahydro-1-(5-isoquinolinylsulfonyl)-, monohydrochloride (9CI);1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride;Fasudilhydrochloride;

Identification

NameFasudil hydrochloride
CAS105628-07-7
SynonymsIsoquinoline,5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1);1H-1,4-Diazepine,hexahydro-1-(5-isoquinolinylsulfonyl)-, monohydrochloride (9CI);1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride;Fasudilhydrochloride;
Molecular FormulaC₁₄H₁₈ClN₃O₂S
Molecular Weight327.82962

Chemical Properties

AppearanceWhite Solid

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
monkey	LD50	intravenous	20mg/kg (20mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 740, 1995.
mouse	LD50	intravenous	67600ug/kg (67.6mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: STRAUB TAIL	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
mouse	LD50	oral	274mg/kg (274mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
mouse	LD50	subcutaneous	124mg/kg (124mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
rat	LD50	intravenous	59900ug/kg (59.9mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
rat	LD50	oral	335mg/kg (335mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
rat	LD50	subcutaneous	123mg/kg (123mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,

supplier list

Shanghai Kairen Industrial Co., Ltd.: Tel:+86-(21)-64120566; Address: Room 107, No.2 dong, 3800 Chunshen Rd(Jinyan Edifice), Minhang, Shanghai 201100,

Wuhan Haizheng Industry & Trade Development Co. Ltd: Tel:86-27-88660577; Address: 27th FL.shuian international masion Bldg.1,Heping Ave.wuhan city

Jiaxing Isen Chemical Co.,Ltd: Tel:86-573-85280080; Address: Address: Room 301, Unit 2, Building 3, Alley 94, East Renmin Road, Pinghu City, Zhejiang Province, China

Wuhan H.X.K Fine Chemicals Co.,LTD: Tel:86-27-59721024; Address: No. 139, hanyang Road, hubei city， Hubei Prov. China 434000

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Chengdu Sino-Strong Pharmaceutical Co.,Ltd.: Tel:0086-28-82666753; Address: 459 West haike road,Cross-straits technological industry park, Wenjiang district, Chengdu, P.R.China

Shulin Li: Tel:86-17083-639935; Address: Huaian East Road Yuhua District Shijiazhuang Hebe

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

FORT ST BIOLOGICAL TECHNOLOGY LIMITED: Tel:86-311-13263231263; Address: jianhua street

Hebei Hongyuan Kang Import and Export Trade Co., Ltd: Tel:86-311-82179998; Address: Jianling Apt.4-2-1702 Yuhua area Shijiazhuang

ShanDong Zhishang Chem: Tel:86-531-67805700; Address: BUILDING 1,NO.88,WEST EXHIBITION ROAD,HIGH-TECH DISTRICT ,JINAN CITY ,SHANDONG PROVINCE,CHINA

Hangzhou J&H Chemical Co., Ltd: Tel:86-571-87396430; Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

Fasudil hydrochloride cas no:105628-07-7

Directory

supplier list