Doxycycline hydrochloride cas no:10592-13-9
Synonyms: 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride (8CI);2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)- (9CI);2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, [4S-(4a,4aa,5a,5aa,6a,12aa)]-;2-Naphthacenecarboxamide,4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,hydrochloride (6CI);6-Deoxyoxytetracycline hydrochloride;6-Desoxy-5-hydroxytetracycline hydrochloride;Deoxy-5-hydroxytetracyclinehydrochloride;Deoxyoxytetracycline hydrochloride;Doxylin;Idocyklin;Vibramycin hyclate;Vibramycin hydrochloride;a-6-Deoxy-5-hydroxytetracyclinehydrochloride;
NameDoxycycline hydrochloride
CAS10592-13-9
Synonyms2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride (8CI);2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)- (9CI);2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, [4S-(4a,4aa,5a,5aa,6a,12aa)]-;2-Naphthacenecarboxamide,4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,hydrochloride (6CI);6-Deoxyoxytetracycline hydrochloride;6-Desoxy-5-hydroxytetracycline hydrochloride;Deoxy-5-hydroxytetracyclinehydrochloride;Deoxyoxytetracycline hydrochloride;Doxylin;Idocyklin;Vibramycin hyclate;Vibramycin hydrochloride;a-6-Deoxy-5-hydroxytetracyclinehydrochloride;
EINECS(EC#)234-198-7
Molecular FormulaC22H24N2O8.HCl
Molecular Weight480.8955 [g/mol]
AppearanceYellow hygroscopic crystalline powder.
storage temp0-6°C
Hazard Xn: Harmful;Xi: Irritant;
Risk R22
Safety
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. An antibacterial agent. When heated to decomposition it emits toxic fumes of NOx and HCl.
Safety information of Doxycycline hydrochloride (CAS NO.10592-13-9):
Hazard Codes? Xn
,Xi
Risk Statements? 22-36/37/38
R22: Harmful if swallowed
R36/37/38: Irritating to eyes, respiratory system and skin?
Safety Statements? 26-36/37
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37: Wear suitable protective clothing and gloves?
WGK Germany? 3
F? 8
HS Code 29413000
| 1. |
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orl-rat LD50:1700?mg/kg
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YACHDS ?? Yakuri to Chiryo. Pharmacology and Therapeutics. 8 (1980),1447. |
| 2. |
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ipr-rat LD50:262?mg/kg
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TXAPA9 ?? Toxicology and Applied Pharmacology. 18 (1971),185. |
| 3. |
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scu-rat LD50:700?mg/kg
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??? |
YACHDS ?? Yakuri to Chiryo. Pharmacology and Therapeutics. 8 (1980),1447. |
| 4. |
??? |
ivn-rat LD50:137?mg/kg
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??? |
YACHDS ?? Yakuri to Chiryo. Pharmacology and Therapeutics. 8 (1980),1447. |
| 5. |
??? |
orl-mus LD50:1890?mg/kg
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??? |
NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),505. |
| 6. |
??? |
scu-mus LD50:700?mg/kg
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??? |
YACHDS ?? Yakuri to Chiryo. Pharmacology and Therapeutics. 8 (1980),1447. |
| 7. |
??? |
ivn-mus LD50:290?mg/kg
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??? |
YACHDS ?? Yakuri to Chiryo. Pharmacology and Therapeutics. 8 (1980),1447. |
