106-49-0|p-ToluidineProducts Supply - Chemical intermediates Network

p-Toluidine cas no:106-49-0

Synonyms: 4-Aminotoluene; 4-Methylaniline; Naphthol As-Kg; Azoic Diazo Component 107; 4-Toluidine; Para Toluidine; PT;

Identification

Namep-Toluidine
CAS106-49-0
Synonyms4-Aminotoluene; 4-Methylaniline; Naphthol As-Kg; Azoic Diazo Component 107; 4-Toluidine; Para Toluidine; PT;
EINECS(EC#)203-403-1
Molecular FormulaC7H9N
Molecular Weight107.15

Chemical Properties

Appearancewhite lustrous plates or leaflets with an amine odour
refractive index1.5636
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1

Safety Data

Hazard T:Toxic
Risk R23/24/25;R36;R40;R43;R50
Safety

Confirmed carcinogen. Poison by ingestion and intraperitoneal routes. Mutation data reported. A severe skin and eye irritant. Flammable when exposed to heat, flame, or oxidizers. Can react vigorously on contact with oxidizing materials. To fight fire, use foam, CO₂, dry chemical. When heated to decomposition it emits highly toxic fumes of NO_x.
Hazard Codes:? Toxic T, Dangerous N
Risk Statements: 23/24/25-36-40-43-50?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.?
R36: Irritating to eyes.?
R40: Limited evidence of a carcinogenic effect.?
R43: May cause sensitization by skin contact.
R50: Very toxic to aquatic organisms.
Safety Statements: 28-36/37-45-61
S28: After contact with skin, wash immediately with plenty of soap-suds.?
S36/37: Wear suitable protective clothing and gloves.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3451 6.1/PG 2
WGK Germany: 2
RTECS: XU3150000
HazardClass: 6.1
PackingGroup of p-Toluidine (CAS NO.106-49-0): II

HS Code 38220000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	42mg/kg (42mg/kg)	?	Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
mouse	LD50	intraperitoneal	50mg/kg (50mg/kg)	?	National Technical Information Service. Vol. AD691-490,
mouse	LD50	oral	330mg/kg (330mg/kg)	?	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(8), Pg. 50, 1981.
quail	LD50	oral	237mg/kg (237mg/kg)	?	Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
rabbit	LD50	oral	270mg/kg (270mg/kg)	?	Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii Vol. #4035-77,
rabbit	LD50	skin	890mg/kg (890mg/kg)	?	BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 31-4/1973,
rat	LC50	inhalation	> 640mg/m3/1H (640mg/m3)	?	BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 31-4/1973,
rat	LD50	oral	336mg/kg (336mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Bromatologia i Chemia Toksykologiczna. Vol. 17, Pg. 51, 1984.

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p-Toluidine cas no:106-49-0

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