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p-Toluidine cas no:106-49-0

Synonyms: 4-Aminotoluene; 4-Methylaniline; Naphthol As-Kg; Azoic Diazo Component 107; 4-Toluidine; Para Toluidine; PT;

Identification
Namep-Toluidine
CAS106-49-0
Synonyms4-Aminotoluene; 4-Methylaniline; Naphthol As-Kg; Azoic Diazo Component 107; 4-Toluidine; Para Toluidine; PT;
EINECS(EC#)203-403-1
Molecular FormulaC7H9N
Molecular Weight107.15
Chemical Properties
Appearancewhite lustrous plates or leaflets with an amine odour
refractive index1.5636
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard T:Toxic
Risk R23/24/25;R36;R40;R43;R50
Safety

Confirmed carcinogen. Poison by ingestion and intraperitoneal routes. Mutation data reported. A severe skin and eye irritant. Flammable when exposed to heat, flame, or oxidizers. Can react vigorously on contact with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of NOx.
Hazard Codes:?ToxicT,DangerousN
Risk Statements: 23/24/25-36-40-43-50?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.?
R36: Irritating to eyes.?
R40: Limited evidence of a carcinogenic effect.?
R43: May cause sensitization by skin contact.
R50: Very toxic to aquatic organisms.
Safety Statements: 28-36/37-45-61
S28: After contact with skin, wash immediately with plenty of soap-suds.?
S36/37: Wear suitable protective clothing and gloves.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3451 6.1/PG 2
WGK Germany: 2
RTECS: XU3150000
HazardClass: 6.1
PackingGroup of p-Toluidine (CAS NO.106-49-0): II


HS Code 38220000

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 42mg/kg (42mg/kg) ? Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
mouse LD50 intraperitoneal 50mg/kg (50mg/kg) ? National Technical Information Service. Vol. AD691-490,
mouse LD50 oral 330mg/kg (330mg/kg) ? Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(8), Pg. 50, 1981.
quail LD50 oral 237mg/kg (237mg/kg) ? Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
rabbit LD50 oral 270mg/kg (270mg/kg) ? Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii Vol. #4035-77,
rabbit LD50 skin 890mg/kg (890mg/kg) ? BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 31-4/1973,
rat LC50 inhalation > 640mg/m3/1H (640mg/m3) ? BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 31-4/1973,
rat LD50 oral 336mg/kg (336mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Bromatologia i Chemia Toksykologiczna. Vol. 17, Pg. 51, 1984.

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