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1,4-Benzoquinone cas no:106-51-4

Synonyms: 2,5-Cyclohexadiene-1,4-dione; Quinone; p-Benzoquinone solution; 1,4-benzoquinone Quinone; Benzoquinone,90%; p-Benzoquinone 98+ % (dried); p-Benzoquinone; P-quinone; PBQ

Identification
Name1,4-Benzoquinone
CAS106-51-4
Synonyms2,5-Cyclohexadiene-1,4-dione; Quinone; p-Benzoquinone solution; 1,4-benzoquinone Quinone; Benzoquinone,90%; p-Benzoquinone 98+ % (dried); p-Benzoquinone; P-quinone; PBQ
EINECS(EC#)203-405-2
Molecular FormulaC6H4O2
Molecular Weight108.1
Chemical Properties
Appearanceyellow to green crystalline solid
refractive indexn20/D 1.453
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard T:Toxic
Risk R23/25;R36/37/38;R50
Safety

Safety Information of?Quinone (CAS NO.106-51-4):
Hazard Codes:T ,N ,Xn , F
Risk Statements:23/25-36/37/38-50-20/21/22-11
23/25:Toxic by inhalation and if swallowed?
36/37/38:Irritating to eyes, respiratory system and skin?
50:Very Toxic to aquatic organisms?
20/21/22:Harmful by inhalation, in contact with skin and if swallowed
11:Highly Flammable??
Safety Statements:26-28-45-61-28A-23-16
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice??
28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)?
61:Avoid release to the environment. Refer to special instructions safety data sheet?
23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer)
16:Keep away from sources of ignition - No smoking???
RIDADR:UN 2587 6.1/PG 2
WGK Germany:3
RTECS:DK2625000
F:8
HazardClass:6.1
PackingGroup:II
Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental tumorigenic data by skin contact. Human mutation data reported. Quinone has a characteristic, irritating odor. Causes severe damage to the skin and mucous membranes by contact with it in the solid state, in solution, or in the form of condensed vapors. Locally, it causes discoloration, severe irritation, erythema, swelling, and the formation of papules and vesicles, whereas prolonged contact may lead to necrosis. When the eyes become involved, it causes dangerous disturbances of vision. The moist material self-heats and decomposes exothermically above 60°C. When heated to decomposition it emits acrid smoke and fumes.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 subcutaneous 296mg/kg (296mg/kg) ? "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 25, 1982.
mouse LD50 intraperitoneal 8500ug/kg (8.5mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Biochemical Pharmacology. Vol. 12, Pg. 885, 1963.
mouse LD50 oral 25mg/kg (25mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
National Technical Information Service. Vol. OTS0571885,
mouse LD50 subcutaneous 93800ug/kg (93.8mg/kg) ? Zeitschrift fuer die Gesamte Innere Medizin und Ihre Grenzgebiete. Vol. 2, Pg. 333, 1947.
rat LD50 intraperitoneal 30mg/kg (30mg/kg) ? Pharmaceutical Bulletin. Vol. 3, Pg. 337, 1955.
rat LD50 intravenous 25mg/kg (25mg/kg) ? Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 8, Pg. 348, 1949.
rat LD50 oral 130mg/kg (130mg/kg) ? Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 8, Pg. 348, 1949.
rat LD50 unreported 5600ug/kg (5.6mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Russian Pharmacology and Toxicology Vol. 41, Pg. 146, 1978.

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