TERGITOL(TM)XH(NONIONIC) cas no:106392-12-5

NameTERGITOL(TM)XH(NONIONIC)
CAS106392-12-5
Synonymsf108; f127; f77; f87; f88; methyloxiranepolymerwithoxiraneblock; oxirane,methyl-,polymerwithoxirane,block
Molecular FormulaC18H36O5X2
Molecular Weight332.48

refractive indexn20/D 1.456

Safety

Low toxicity by ingestion and skin contact. When heated to decomposition it emits acrid smoke and irritating vapors.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	420mg/kg (420mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 34(Suppl), Pg. 533, 1982.
mouse	LD50	intravenous	129mg/kg (129mg/kg)		Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 12, Pg. 569, 1993.
mouse	LD50	intravenous	1gm/kg (1000mg/kg)		Microvascular Research. Vol. 8, Pg. 320, 1974.
mouse	LD50	intravenous	3gm/kg (3000mg/kg)		Drugs in Japan Vol. 6, Pg. 797, 1982.
mouse	LD50	oral	> 30300ug/kg (30.3mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 2291, 1981.
mouse	LD50	oral	1830mg/kg (1830mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 34(Suppl), Pg. 533, 1982.
mouse	LD50	oral	15gm/kg (15000mg/kg)		Bollettino Chimico Farmaceutico. Vol. 101, Pg. 173, 1962.
mouse	LD50	subcutaneous	5500mg/kg (5500mg/kg)		Drugs in Japan Vol. 6, Pg. 797, 1982.
mouse	LD50	unreported	400mg/kg (400mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	530mg/kg (530mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	750mg/kg (750mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	830mg/kg (830mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	1250mg/kg (1250mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	1400mg/kg (1400mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	2250mg/kg (2250mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	2700mg/kg (2700mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	3gm/kg (3000mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	3750mg/kg (3750mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	4200mg/kg (4200mg/kg)		United States Patent Document. Vol. #4043344,
mouse	LD50	unreported	> 5gm/kg (5000mg/kg)		United States Patent Document. Vol. #4043344,
rabbit	LD50	skin	> 5gm/kg (5000mg/kg)		Union Carbide Data Sheet. Vol. 7/14/1965,
rat	LD50	intraperitoneal	320mg/kg (320mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: OTHER CHANGES BEHAVIORAL: ATAXIA	National Technical Information Service. Vol. OTS0540972,
rat	LD50	intraperitoneal	1140mg/kg (1140mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 34(Suppl), Pg. 533, 1982.
rat	LD50	intravenous	7500mg/kg (7500mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 1204, 1981.
rat	LD50	oral	> 30300ug/kg (30.3mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 2291, 1981.
rat	LD50	oral	2300mg/kg (2300mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 34(Suppl), Pg. 533, 1982.
rat	LD50	oral	5gm/kg (5000mg/kg)	VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA	Wyandotte Chemicals Corporation Reports.
rat	LD50	oral	5gm/kg (5000mg/kg)	VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA	Wyandotte Chemicals Corporation Reports.
rat	LD50	oral	5gm/kg (5000mg/kg)	VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Wyandotte Chemicals Corporation Reports.
rat	LD50	oral	9380mg/kg (9380mg/kg)		"Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972Vol. -, Pg. 297, 1972.
rat	LD50	oral	22400mg/kg (22400mg/kg)		Union Carbide Data Sheet. Vol. 7/14/1965,
rat	LD50	subcutaneous	6900mg/kg (6900mg/kg)		Drugs in Japan Vol. 6, Pg. 797, 1982.