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2-Methyl-2,4-pentanediol cas no:107-41-5

Synonyms: 2-Methylpentane-2,4-diol; Diolane; Hexylene glycol; HEXYLENE GLYCOL (2-METHYL-2,4-PENTANEDIOL; Isol; Pinakon;

Identification
Name2-Methyl-2,4-pentanediol
CAS107-41-5
Synonyms2-Methylpentane-2,4-diol; Diolane; Hexylene glycol; HEXYLENE GLYCOL (2-METHYL-2,4-PENTANEDIOL; Isol; Pinakon;
EINECS(EC#)203-489-0
Molecular FormulaC6H14O2
Molecular Weight118.17
Chemical Properties
AppearanceOily colorless liquid with a mild sweet odor
refractive index1.426-1.428
storage temp2-8°C
Sensitive Hygroscopic
Safety Data

Hazard Xi:Irritant
Risk R36/38
Safety

Hazard Codes:?IrritantXi
Risk Statements: 36/38
R36/38:Irritating to eyes and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
WGK Germany: 1
RTECS: SA0810000
F: 3-23
HS Code: 29053910
Moderately toxic by ingestion and intraperitoneal routes. Mildly toxic by skin contact. Human systemic effects by inhalation: conjunctiva and other eye, olfactory, and pulmonary changes. Mutation data reported. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemicals. When heated to decomposition it emits acrid smoke and fumes.?See also GLYCOLS, POLYETHYLENE, MONO((1,1,3,3-TETRAMETHYLBUTYL)PHENYL) ETHER; GLYCOLS, POLYETHYLENE MONO(TRI-METHYLNONYL); GLYCOLS, POLYETHYLENE POLYPROPYL-ENE, MONOBUTYL ETHER (nonionic); GLYCOLS, POLYTETRAMETHYLENE.


HS Code 29053910

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 2800mg/kg (2800mg/kg) BEHAVIORAL: GENERAL ANESTHETIC
BEHAVIORAL: MUSCLE WEAKNESS
LIVER: OTHER CHANGES
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 4, Pg. 142, 1945.
human TCLo inhalation 50ppm/15M (50ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 312, 1969.
human TCLo inhalation 50ppm (50ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 262, 1946.
mouse LD50 intraperitoneal 1299mg/kg (1299mg/kg) ? Shell Chemical Company. Unpublished Report. Vol. -, Pg. 5, 1961.
mouse LD50 oral 3097mg/kg (3097mg/kg) ? Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 669, 1956.
rabbit LD50 oral 3200mg/kg (3200mg/kg) BEHAVIORAL: GENERAL ANESTHETIC
BEHAVIORAL: MUSCLE WEAKNESS
LIVER: OTHER CHANGES
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 4, Pg. 142, 1945.
rabbit LD50 skin 8560uL/kg (8.56mL/kg) ? "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969.
rabbit LD50 subcutaneous 13gm/kg (13000mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Food and Cosmetics Toxicology. Vol. 16, Pg. 777, 1978.
rat LC50 inhalation > 310mg/m3/1H (310mg/m3) ? BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 12-4/1970,
rat LD50 oral 3700mg/kg (3700mg/kg) ? Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 68, 1974.
rat LDLo intraperitoneal 1500mg/kg (1500mg/kg) BEHAVIORAL: GENERAL ANESTHETIC
GASTROINTESTINAL: OTHER CHANGES
KIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED
Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 150, 1959.

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