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1-Methoxy-2-propanol cas no:107-98-2

Synonyms: 1-Methoxy-2-hydroxypropane;Dowtherm 209;Propylene glycol methyl ether;Propylenglykol-monomethylaether;Dowanol-33B;1-methoxypropan-2-ol;.alpha.-Propylene glycol monomethyl ether;2-Methoxy-1-methylethanol;2-Propanol,1-methoxy-;2-Propanol, 1-methoxy-;Propylene Glycol Monomethyl Ether(PM):;Propylene Glycol Monomethyl Ether;Methoxyisopropanol;

Identification
Name1-Methoxy-2-propanol
CAS107-98-2
Synonyms1-Methoxy-2-hydroxypropane;Dowtherm 209;Propylene glycol methyl ether;Propylenglykol-monomethylaether;Dowanol-33B;1-methoxypropan-2-ol;.alpha.-Propylene glycol monomethyl ether;2-Methoxy-1-methylethanol;2-Propanol,1-methoxy-;2-Propanol, 1-methoxy-;Propylene Glycol Monomethyl Ether(PM):;Propylene Glycol Monomethyl Ether;Methoxyisopropanol;
EINECS(EC#)203-539-1
Molecular FormulaC4H10O2
Molecular Weight90.12
Chemical Properties
Appearancecolourless liquid
refractive index1.402-1.404
storage tempKeep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Keep containers tightly closed.
Sensitive Hygroscopic
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3
Safety Data

Risk R10
Safety

Risk Statements of Methoxy propanol (CAS NO.107-98-2): 10?
R10: Flammable
Safety Statements: 24-26-24/25?
S24: Avoid contact with skin
S26: In case of contact with eyes, rinse immediately with plenty of WATER and seek medical advice
RIDADR: UN 3092 3/PG 3
WGK Germany: 1
RTECS: UB7700000
HazardClass: 3
PackingGroup: III
HS Code: 29094919?


HS Code 29094919

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 2gm/kg (2000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 569, 1972.
?
dog LD50 oral 5gm/kg (5000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 569, 1972.
?
guinea pig LCLo inhalation 15000ppm/7H (15000ppm) BEHAVIORAL: SLEEP AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 9, Pg. 509, 1954.
human TCLo inhalation 3000ppm (3000ppm) SENSE ORGANS AND SPECIAL SENSES: TUMORS: OLFACTION

BEHAVIORAL: GENERAL ANESTHETIC

GASTROINTESTINAL: NAUSEA OR VOMITING
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 105, 1974.
mouse LD intraperitoneal > 500mg/kg (500mg/kg) ? "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 4, Pg. 110, 1952.
mouse LD50 intravenous 5300mg/kg (5300mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 569, 1972.
?
mouse LD50 oral 11700mg/kg (11700mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 569, 1972.
?
rabbit LCLo inhalation 15000ppm/7H (15000ppm) ? AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 9, Pg. 509, 1954.
rabbit LD50 intravenous 1200mg/kg (1200mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 569, 1972.
?
rabbit LD50 oral 5700mg/kg (5700mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 569, 1972.
?
rabbit LD50 skin 13gm/kg (13000mg/kg) ? Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 105, 1974.
rabbit LD50 subcutaneous 5gm/kg (5000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 569, 1972.
?
rat LC50 inhalation 10000ppm/5H (10000ppm) ? Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 105, 1974.
rat LD50 intraperitoneal 3720mg/kg (3720mg/kg) ? "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3977, 1982.
rat LD50 intravenous 4200mg/kg (4200mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 569, 1972.
?
rat LD50 subcutaneous 7800mg/kg (7800mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 569, 1972.
?
rat LDLo oral 3739mg/kg (3739mg/kg) SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA
National Technical Information Service. Vol. OTS0520402

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