107007-99-8|Granisetron hydrochlorideProducts Supply

Granisetron hydrochloride cas no:107007-99-8

Synonyms: 1H-Indazole-3-carboxamide,1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, monohydrochloride(9CI);BRL 43694A;Kytril;1H-Indazole-3-carboxamide,1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, hydrochloride(1:1);1H-Indazole-3-carboxamide,1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, monohydrochloride, endo-;

Identification

NameGranisetron hydrochloride
CAS107007-99-8
Synonyms1H-Indazole-3-carboxamide,1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, monohydrochloride(9CI);BRL 43694A;Kytril;1H-Indazole-3-carboxamide,1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, hydrochloride(1:1);1H-Indazole-3-carboxamide,1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, monohydrochloride, endo-;
Molecular FormulaC₁₈H₂₅ClN₄O
Molecular Weight348.87

Chemical Properties

AppearanceWhite to Off-White Crystalline Solid
refractive index1.69
storage tempRoom temp

Safety Data

Hazard Xn: Harmful;Xi: Irritant;
Risk R22
Safety

Hazard Codes:? Harmful Xn, Irritant Xi
Risk Statements: 22-62-37/38-36/37/38-36?
R22:Harmful if swallowed.?
R62:Risk of impaired fertility.?
R37/38:Irritating to respiratory system and skin.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R36:Irritating to eyes.
Safety Statements: 26-36-37?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.?
S37:Wear suitable gloves.
RTECS: NK7882200

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	3mg/kg (3mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: TREMOR GASTROINTESTINAL: NAUSEA OR VOMITING	Yakkyoku. Pharmacy. Vol. 43, Pg. 589, 1992.
dog	LDLo	oral	15mg/kg (15mg/kg)	BEHAVIORAL: TREMOR GASTROINTESTINAL: NAUSEA OR VOMITING	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 37, Pg. 2697, 1995.
mouse	LD50	intravenous	17mg/kg (17mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 4991, 1990.
mouse	LD50	oral	350mg/kg (350mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 740, 1995.
rat	LD50	intravenous	14mg/kg (14mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 4991, 1990.
rat	LD50	oral	350mg/kg (350mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 740, 1995.

supplier list

CNCCC SICHUAN IMPORT/EXPORT CO.,LTD.: Tel:; Address: 8C Ruili, Palm Garden, 153 KeHua North Rd, Chengdu,Sichuan, P.R.China

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

Qufu Hongly Chemical Industry Co.,Ltd.: Tel:; Address: 5F,C 5F,C Flat Shengcheng International Trade Building No.49 Datong Road Qufu Shandong China

ZunAn Commerce & Industrial Co., Ltd.: Tel:锛?86-755-82910159, 82910995,82910996; Address: Room 3007, United Plaza A, Binhe Road 5022, Shenzhen, P.R.China

Depew Fine Chemical Co.,Ltd.: Tel:+86-571-87630650, 87630656, 87630657; Address: Room 202,No.317 Wantang Road,Hangzhou,China

FOYO: Tel:; Address: No.433 Wuyi Road(N),Hutang town,Wujin,Chang-Zhou,JiangSu China

Beijing Lunarsun Pharmaceutical Co.Ltd.: Tel:086-10-81760039 80771377 80771378 80771379 81760170 81760171 81760172; Address: C1-802, Yangguangguangchang, Anli Road No.68 ,Chaoyang District , 100101 , Beijing , P.R.China

Changzhou Ruiming Pharmaceutical Co., Ltd.: Tel:+86-(519)-2731357; Address: Sudu Town, Jintan, Jiangsu 213232,

Ningbo Victory & Prosperity Chemistry CO.,LTD.: Tel:+86-(574)-27666767; Address: 21/F, No.11 Bldg, Xin Tian Di, NO 689, Shi Ji Road, NINGBO 315040,

Vesino Industrial Co., Ltd.: Tel:86-22-27455635; Address: No.4 Xinglanyuan Building, Changjiang Road, Tianjin 300193,

Hetero Drugs Ltd.,: Tel:+91-(40)-23704923; Address: H.No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh 500 018,

Synasia Fine Chemicals Inc.: Tel:+1-(732)-205-9880; Address: 240 Amboy Avenue, Metuchen, New Jersey 08840,

Beijing Lunarsun Pharmaceutical Co., Ltd.: Tel:+86-(10)-80771328, 80771377; Address: C1-802, Yangguangguangchang, Anli Road No.68, Chaoyang District, Beijing 100101,

Sanmen Eastsky Pharmaceutical Co., Ltd: Tel:+86-(576)-83510058; Address: Room 8402, Saigete Garden, Dahutang Development Zone, Sanmen, Zhejiang 317100,

Changzhou Kessie Chemical Co., Ltd.: Tel:+86-(519)-84890212; Address: No-13, Guanghua West Road, Changzhou, Jiangsu,

Granisetron hydrochloride cas no:107007-99-8

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