107007-99-8|Granisetron hydrochlorideProducts Supply

Granisetron hydrochloride cas no:107007-99-8

Synonyms: 1H-Indazole-3-carboxamide,1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, monohydrochloride(9CI);BRL 43694A;Kytril;1H-Indazole-3-carboxamide,1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, hydrochloride(1:1);1H-Indazole-3-carboxamide,1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, monohydrochloride, endo-;

Identification

NameGranisetron hydrochloride
CAS107007-99-8
Synonyms1H-Indazole-3-carboxamide,1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, monohydrochloride(9CI);BRL 43694A;Kytril;1H-Indazole-3-carboxamide,1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, hydrochloride(1:1);1H-Indazole-3-carboxamide,1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, monohydrochloride, endo-;
Molecular FormulaC₁₈H₂₅ClN₄O
Molecular Weight348.87

Chemical Properties

AppearanceWhite to Off-White Crystalline Solid
refractive index1.69
storage tempRoom temp

Safety Data

Hazard Xn: Harmful;Xi: Irritant;
Risk R22
Safety

Hazard Codes:? Harmful Xn, Irritant Xi
Risk Statements: 22-62-37/38-36/37/38-36?
R22:Harmful if swallowed.?
R62:Risk of impaired fertility.?
R37/38:Irritating to respiratory system and skin.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R36:Irritating to eyes.
Safety Statements: 26-36-37?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.?
S37:Wear suitable gloves.
RTECS: NK7882200

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	3mg/kg (3mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: TREMOR GASTROINTESTINAL: NAUSEA OR VOMITING	Yakkyoku. Pharmacy. Vol. 43, Pg. 589, 1992.
dog	LDLo	oral	15mg/kg (15mg/kg)	BEHAVIORAL: TREMOR GASTROINTESTINAL: NAUSEA OR VOMITING	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 37, Pg. 2697, 1995.
mouse	LD50	intravenous	17mg/kg (17mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 4991, 1990.
mouse	LD50	oral	350mg/kg (350mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 740, 1995.
rat	LD50	intravenous	14mg/kg (14mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 4991, 1990.
rat	LD50	oral	350mg/kg (350mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 740, 1995.

supplier list

Shanghai bio-uchem I/E Co., Ltd.: Tel:; Address: 15/FRoom E No .1381-1383 Dong Fang Rd.Pu Dong.Shanghai,China

Chemagis: Tel:; Address:

Hangzhou Pharma & Chem Co., Ltd.: Tel:+86-(571)-87040515; Address: Rm.1201,Qinglian Bldg.No,139 Qingchun Rd, Hangzhou, Zhejiang 310003,

Qilong Chemical Co., Ltd.: Tel:86-574-63858500; Address: No.586, Jiangnan Road,High-tech Park, Ningbo, Zhejiang 315040,

S.S.T. Corporation: Tel:+1-(973)-473-4300; Address: 635 Brighton Road, Clifton, New Jersey 07012,

Synasia Fine Chemicals Inc.: Tel:+1-(732)-205-9880; Address: 240 Amboy Avenue, Metuchen, New Jersey 08840,

Hubei Biocause Pharmaceutical Co. Ltd: Tel:+86-(27)-65651730; Address: c-7th Floor, Golden trade center, Guantong Garden, 115 Wujia, Jianghan District, Wuhan, Hubei 430023,

Sanmen Eastsky Pharmaceutical Co., Ltd: Tel:+86-(576)-83510058; Address: Room 8402, Saigete Garden, Dahutang Development Zone, Sanmen, Zhejiang 317100,

Changzhou Kessie Chemical Co., Ltd.: Tel:+86-(519)-84890212; Address: No-13, Guanghua West Road, Changzhou, Jiangsu,

Xiamen Kaijia Imp. & Exp. Co., Ltd.: Tel:+86-(592)-5101177; Address: Room406 Luhui Building No. 65 Haitian Road, Huli Xiamen 361006,

Egypharma: Tel:+20-(2)-22871991; Address: 24 Abbas El Akkad Street, Nasr, Cairo,

Alchemy Importers, Inc.: Tel:+1-(856)-308-3828; Address: 9 Black Latch Lane, Cherry Hill, New Jersey 08003,

ACIC Fine Chemicals Inc.: Tel:+1-(800)-265-6727; Address: 11772 West Sample Road, Coral Springs, Florida 33065,

Tecoland Corporation: Tel:+1-(732)-603-9577; Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,

Chongqing Trust Long Co., Ltd.: Tel:+86-(23)-6760-5657, 6791-0421, 6707-4306; Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist, Chongqing 401147,

Granisetron hydrochloride cas no:107007-99-8

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