Perindopril erbumine cas no:107133-36-8
Synonyms: (2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester, compound with tert-butylamine (1:1);Aceon (TN);S 9490-3;Perindopril erbumine/tert-butylamine;Perindopril erbumine [USAN];(2S,3aS,7aS)-1-{(2S)-2-[(1S)-1-(ethoxycarbonyl)butylamino]propanoyl}octahydro-1H-indole-2-carboxylic acid--2-methylpropan-2-amine (1/1);(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-ethoxycarbonylbutyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid; 2-methylpropan-2-amine;S-9490-3;1H-Indole-2-carboxylic acid,1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)- butyl]amino]-1-oxopropyl]octahydro-,(2S,3aS,- 7aS)-,compd. with 2-methyl-2-propanamine (1:1);1H-Indole-2-carboxylic acid, 1-(2-((1-(ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydro-, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))-, compd. with 2-methyl-2-propanamine (1:1);McN-A-2833-109;Perindopril erbumine (JAN/USAN);MCN-A 2833-109;Perindopril tert-butylamine;Perindopril;
NamePerindopril erbumine
CAS107133-36-8
Synonyms(2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester, compound with tert-butylamine (1:1);Aceon (TN);S 9490-3;Perindopril erbumine/tert-butylamine;Perindopril erbumine [USAN];(2S,3aS,7aS)-1-{(2S)-2-[(1S)-1-(ethoxycarbonyl)butylamino]propanoyl}octahydro-1H-indole-2-carboxylic acid--2-methylpropan-2-amine (1/1);(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-ethoxycarbonylbutyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid; 2-methylpropan-2-amine;S-9490-3;1H-Indole-2-carboxylic acid,1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)- butyl]amino]-1-oxopropyl]octahydro-,(2S,3aS,- 7aS)-,compd. with 2-methyl-2-propanamine (1:1);1H-Indole-2-carboxylic acid, 1-(2-((1-(ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydro-, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))-, compd. with 2-methyl-2-propanamine (1:1);McN-A-2833-109;Perindopril erbumine (JAN/USAN);MCN-A 2833-109;Perindopril tert-butylamine;Perindopril;
Molecular FormulaC19H32N2O5.C4H11N
Molecular Weight441.69
Appearancewhite solid
Hazard Xi
Risk R36/37/38
Safety
A poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx Hazard codes: Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36: Wear suitable protective clothing
| 1. |
??? |
orl-rat LD :>2500?mg/kg
|
??? |
YAKUD5 ?? Gekkan Yakuji. Pharmaceuticals Monthly. 40 (1998),3147. |
| 2. |
??? |
ivn-rat LD50:323?mg/kg
|
??? |
YAKUD5 ?? Gekkan Yakuji. Pharmaceuticals Monthly. 40 (1998),3147. |
| 3. |
??? |
orl-mus LD :>2500?mg/kg
|
??? |
YAKUD5 ?? Gekkan Yakuji. Pharmaceuticals Monthly. 40 (1998),3147. |
| 4. |
??? |
ivn-mus LD50:323?mg/kg
|
??? |
YAKUD5 ?? Gekkan Yakuji. Pharmaceuticals Monthly. 40 (1998),3147. |
