108-94-1|CyclohexanoneProducts Supply - Chemical intermediates Network

Cyclohexanone cas no:108-94-1

Synonyms: Anon; caswellno270; Cicloesanone; Cykloheksanon; cykloheksanon(polish); epapesticidechemicalcode025902; Hexanon; Hytrol O

Identification

NameCyclohexanone
CAS108-94-1
SynonymsAnon; caswellno270; Cicloesanone; Cykloheksanon; cykloheksanon(polish); epapesticidechemicalcode025902; Hexanon; Hytrol O
EINECS(EC#)203-631-1
Molecular FormulaC6H10O
Molecular Weight98.14

Chemical Properties

AppearanceColourless liquid.
refractive index1.445-1.456
storage tempFlammables area.

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass3

Safety Data

Hazard Xn:Harmful
Risk R10;R20
Safety Hazard Codes: Harmful Xn
Risk Statements: 10-20
R10:Flammable.
R20:Harmful by inhalation.
Safety Statements: 25
S25:Avoid contact with eyes.
Cyclohexanone (CAS NO.108-94-1) is not carcinogenic and is only moderately toxic, with a TLV of 25 ppm for the vapor. It is an irritant.A recent study of plastic tubing used in medical procedures that circulate blood outside the body suggests a link between this compound and decreased heart function, swelling, loss of taste and short term memory loss.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
frog	LDLo	subcutaneous	1900mg/kg (1900mg/kg)	AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903.
guinea pig	LCLo	inhalation	400ppm/4H (400ppm)		National Technical Information Service. Vol. AD-A066-307,
guinea pig	LDLo	intraperitoneal	760mg/kg (760mg/kg)		National Technical Information Service. Vol. AD-A066-307,
human	TCLo	inhalation	75ppm (75ppm)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943.
mammal (species unspecified)	LC50	inhalation	25gm/m3 (25000mg/m3)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified)	LD50	oral	3gm/kg (3000mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
monkey	LDLo	intravenous	284mg/kg (284mg/kg)		Toxicology and Applied Pharmacology. Vol. 37, Pg. 115, 1976.
mouse	LCLo	inhalation	19200mg/m3/90 (19200mg/m3)	GASTROINTESTINAL: OTHER CHANGES	Toxicology and Applied Pharmacology. Vol. 49, Pg. 525, 1979.
mouse	LD50	intraperitoneal	1230mg/kg (1230mg/kg)	GASTROINTESTINAL: OTHER CHANGES	Toxicology and Applied Pharmacology. Vol. 49, Pg. 525, 1979.
mouse	LD50	oral	1400mg/kg (1400mg/kg)		National Technical Information Service. Vol. AD-A066-307,
mouse	LDLo	subcutaneous	1300mg/kg (1300mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ATAXIA	Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903.
rabbit	LD50	intraperitoneal	1540mg/kg (1540mg/kg)	GASTROINTESTINAL: OTHER CHANGES	Toxicology and Applied Pharmacology. Vol. 49, Pg. 525, 1979.
rabbit	LD50	skin	1mL/kg (1mL/kg)		American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rabbit	LDLo	oral	1600mg/kg (1600mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC	Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 199, 1943.
rat	LC50	inhalation	8000ppm/4H (8000ppm)		Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 18, 1974.
rat	LD50	intraperitoneal	1130mg/kg (1130mg/kg)	GASTROINTESTINAL: OTHER CHANGES	Toxicology and Applied Pharmacology. Vol. 49, Pg. 525, 1979.
rat	LD50	oral	1620uL/kg (1.62mL/kg)		American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rat	LD50	subcutaneous	2170mg/kg (2170mg/kg)		Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 415, 1943.
rat	LDLo	intravenous	568mg/kg (568mg/kg)		Toxicology and Applied Pharmacology. Vol. 37, Pg. 115, 1976.

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Cyclohexanone cas no:108-94-1

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