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Cyclohexanone cas no:108-94-1

Synonyms: Anon; caswellno270; Cicloesanone; Cykloheksanon; cykloheksanon(polish); epapesticidechemicalcode025902; Hexanon; Hytrol O

Identification
NameCyclohexanone
CAS108-94-1
SynonymsAnon; caswellno270; Cicloesanone; Cykloheksanon; cykloheksanon(polish); epapesticidechemicalcode025902; Hexanon; Hytrol O
EINECS(EC#)203-631-1
Molecular FormulaC6H10O
Molecular Weight98.14
Chemical Properties
AppearanceColourless liquid.
refractive index1.445-1.456
storage tempFlammables area.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3
Safety Data

Hazard Xn:Harmful
Risk R10;R20
Safety Hazard Codes:HarmfulXn
Risk Statements: 10-20
R10:Flammable.
R20:Harmful by inhalation.
Safety Statements: 25
S25:Avoid contact with eyes.
Cyclohexanone (CAS NO.108-94-1) is not carcinogenic and is only moderately toxic, with a TLV of 25 ppm for the vapor. It is an irritant.A recent study of plastic tubing used in medical procedures that circulate blood outside the body suggests a link between this compound and decreased heart function, swelling, loss of taste and short term memory loss.

Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo subcutaneous 1900mg/kg (1900mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903.
guinea pig LCLo inhalation 400ppm/4H (400ppm) National Technical Information Service. Vol. AD-A066-307,
guinea pig LDLo intraperitoneal 760mg/kg (760mg/kg) National Technical Information Service. Vol. AD-A066-307,
human TCLo inhalation 75ppm (75ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943.
mammal (species unspecified) LC50 inhalation 25gm/m3 (25000mg/m3) Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified) LD50 oral 3gm/kg (3000mg/kg) Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
monkey LDLo intravenous 284mg/kg (284mg/kg) Toxicology and Applied Pharmacology. Vol. 37, Pg. 115, 1976.
mouse LCLo inhalation 19200mg/m3/90 (19200mg/m3) GASTROINTESTINAL: OTHER CHANGES Toxicology and Applied Pharmacology. Vol. 49, Pg. 525, 1979.
mouse LD50 intraperitoneal 1230mg/kg (1230mg/kg) GASTROINTESTINAL: OTHER CHANGES Toxicology and Applied Pharmacology. Vol. 49, Pg. 525, 1979.
mouse LD50 oral 1400mg/kg (1400mg/kg) National Technical Information Service. Vol. AD-A066-307,
mouse LDLo subcutaneous 1300mg/kg (1300mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: ATAXIA
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903.
rabbit LD50 intraperitoneal 1540mg/kg (1540mg/kg) GASTROINTESTINAL: OTHER CHANGES Toxicology and Applied Pharmacology. Vol. 49, Pg. 525, 1979.
rabbit LD50 skin 1mL/kg (1mL/kg) American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rabbit LDLo oral 1600mg/kg (1600mg/kg) BEHAVIORAL: GENERAL ANESTHETIC Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 199, 1943.
rat LC50 inhalation 8000ppm/4H (8000ppm) Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 18, 1974.
rat LD50 intraperitoneal 1130mg/kg (1130mg/kg) GASTROINTESTINAL: OTHER CHANGES Toxicology and Applied Pharmacology. Vol. 49, Pg. 525, 1979.
rat LD50 oral 1620uL/kg (1.62mL/kg) American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rat LD50 subcutaneous 2170mg/kg (2170mg/kg) Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 415, 1943.
rat LDLo intravenous 568mg/kg (568mg/kg) Toxicology and Applied Pharmacology. Vol. 37, Pg. 115, 1976.

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