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Butanamide,N-(4-ethoxyphenyl)-3-hydroxy- cas no:1083-57-4

Synonyms: p-Butyrophenetidide,3-hydroxy- (6CI,7CI,8CI);(?à)-Bucetin;3-Hydroxy-p-butyrophenetidide;Betadid;Bucetin;N-(b-Hydroxybutyryl)-p-phenetidine;p-Ethoxy-N-(b-hydroxybutyryl)aniline;b-Hydroxybutyric acidp-phenetidide;156674-12-3;

Identification
NameButanamide,N-(4-ethoxyphenyl)-3-hydroxy-
CAS1083-57-4
Synonymsp-Butyrophenetidide,3-hydroxy- (6CI,7CI,8CI);(?à)-Bucetin;3-Hydroxy-p-butyrophenetidide;Betadid;Bucetin;N-(b-Hydroxybutyryl)-p-phenetidine;p-Ethoxy-N-(b-hydroxybutyryl)aniline;b-Hydroxybutyric acidp-phenetidide;156674-12-3;
EINECS(EC#)214-109-8
Molecular FormulaC12H17 N O3
Molecular Weight223.30
Chemical Properties
refractive index1.558
Safety Data

Hazard T
Safety

Moderately toxic by ingestion and intraperitoneal routes. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When heated to decomposition Bucetin (CAS NO.1083-57-4) emits toxic fumes of NOx.
Hazard Codes: ToxicT
Risk Statements: 45-46-20/21/22 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R45:May cause cancer. 
R46:May cause heritable genetic damage.
Safety Statements: 53-22-36/37/39-45 
S22:Do not breathe dust. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S53:Avoid exposure - obtain special instructions before use.


Toxicity
1.    

mma-sat 2 µmol/plate

    CPBTAL    Chemical and Pharmaceutical Bulletin. 33 (1985),2877.
2.    

orl-rat LD50:7 g/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 15 (1965),727.
3.    

orl-mus LD50:2800 mg/kg

    NYKZAU    Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 62 (1966),123.
4.    

ipr-mus LD50:790 mg/kg

    NYKZAU    Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 62 (1966),123.

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