2H-1-Benzothiopyran-7-sulfonamide,3,4-dihydro-6-methyl-, 1,1-dioxide cas no:1084-65-7

Name2H-1-Benzothiopyran-7-sulfonamide,3,4-dihydro-6-methyl-, 1,1-dioxide
CAS1084-65-7
SynonymsThiochroman-7-sulfonamide,6-methyl-, 1,1-dioxide (7CI,8CI); 6-Methyl-7-sulfamide-thiochromane1,1-dioxode; 6-Methyl-7-sulfamoylthiochroman 1,1-dioxide;6-Methylthiochroman-7-sulfonamide 1,1-dioxide; Arresten; E 103E; Fontilix;Meticran; Meticrane; SD 171-02; SD 17102
EINECS(EC#)214-112-4
Molecular FormulaC10H13 N O4 S2
Molecular Weight275.36

refractive index1.601

Safety

Poison by intravenous route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SO_x and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	10gm/kg (10000mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 217, 1974.
mouse	LD50	intravenous	325mg/kg (325mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 217, 1974.
mouse	LD50	oral	> 20gm/kg (20000mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3560, 1973.
mouse	LD50	subcutaneous	> 20gm/kg (20000mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3560, 1973.
rat	LD50	intravenous	445mg/kg (445mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 217, 1974.
rat	LD50	oral	> 16gm/kg (16000mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3560, 1973.
rat	LD50	subcutaneous	> 15gm/kg (15000mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3560, 1973.