109581-93-3|Tacrolimus monohydrateProducts Supply - Chemical intermediates Network

Tacrolimus monohydrate cas no:109581-93-3

Synonyms: 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)- (9CI);15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate,[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;Tsukubaenolide hydrate;

Identification

NameTacrolimus monohydrate
CAS109581-93-3
Synonyms15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)- (9CI);15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate,[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;Tsukubaenolide hydrate;
Molecular FormulaC₄₄H₆₉NO₁₂^.H₂O
Molecular Weight822.16

Chemical Properties

storage temp?20°C

Safety Data

Hazard T: Toxic;
Risk R25
Safety

Hazard Codes of Tacrolimus monohydrate (CAS NO.109581-93-3): T
Risk Statements:?25
R25 :Toxic if swallowed.
Safety Statements:?45
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LD50	intravenous	23600ug/kg (23.6mg/kg)	?	Drugs in Japan Vol. -, Pg. 720, 1995.
rat	LD50	oral	134mg/kg (134mg/kg)	?	Drugs in Japan Vol. -, Pg. 720, 1995.

supplier list

Sinoway Chemical Co., Ltd.: Tel:; Address: 16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China

Jinan Laien Chemical Co., Ltd: Tel:86-543-5081965; Address: 28 Gongye Rd. South, Jinan High-tech Zone, Jinan, China

Beijing huafeng united technology co.,ltd: Tel:; Address: NO.18 Jianguo RD, Chaoyang district, Beijing, China

Taizhou Xingcheng Chempharm Co., Ltd.: Tel:+86-(576)-88886292, 88525005; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road, Taizhou, Zhejiang 318000,

Biocon India: Tel:91 80 2808 2808; Address: 20th KM, Hosur Road,Electronics City,Bangalore, India - 560 100

ZHONGBEI NORTHLAND BIO-CHEM INDUSTRY CO., LTD.: Tel:+86-452-6197139; Address: SONGLING DISTRICT, JIAGEDAQI CITY, DAXINGANLING, HEILONGJIANG PROVINCE, CHINA

Guangzhou WeiBo Chemical Co., Ltd.: Tel:020-33640779 32416961; Address: NO.1002-39,jinbi building,shijinshicha road,baiyun district,guanghzou city

NEXFAR Limited - China: Tel:86-571-85574334; Address: Central Building 304, # No.271, Hushu Nan Road

Sinosource Pharma Limited: Tel:+86-(20)-85581896, 33698005; Address: 1-19L, Canada Garden, Tianhe, Guangzhou, Guangdong 510665,

Xingcheng Chemphar Co.,Ltd.: Tel:0086-576-88559905; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China

HangZhou Puris Biotechnology Ltd.: Tel:86-571-18663102648; Address: Wantang RD262, Hangzhou,Zhejiang P.R,China

Struchem Co Ltd: Tel:86-512-63009836; Address: No. 2358 Chang'an Rd, Wujiang City, JiangSu Province, China 215200

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road Shirley, NY 11967, USA

Shenzhen Simeiquan Biotechnology Co.Ltd: Tel:86-20-18102838259; Address: Bao'an Bao'an District of Shenzhen City manhole st

Hebei Ruishun Trade and Industry Co., Ltd.: Tel:86-311-67266192; Address: Huai An Road,Shijiazhuang City, China

Tacrolimus monohydrate cas no:109581-93-3

Directory

supplier list