109581-93-3|Tacrolimus monohydrateProducts Supply - Chemical intermediates Network

Tacrolimus monohydrate cas no:109581-93-3

Synonyms: 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)- (9CI);15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate,[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;Tsukubaenolide hydrate;

Identification

NameTacrolimus monohydrate
CAS109581-93-3
Synonyms15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)- (9CI);15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate,[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;Tsukubaenolide hydrate;
Molecular FormulaC₄₄H₆₉NO₁₂^.H₂O
Molecular Weight822.16

Chemical Properties

storage temp?20°C

Safety Data

Hazard T: Toxic;
Risk R25
Safety

Hazard Codes of Tacrolimus monohydrate (CAS NO.109581-93-3): T
Risk Statements:?25
R25 :Toxic if swallowed.
Safety Statements:?45
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LD50	intravenous	23600ug/kg (23.6mg/kg)	?	Drugs in Japan Vol. -, Pg. 720, 1995.
rat	LD50	oral	134mg/kg (134mg/kg)	?	Drugs in Japan Vol. -, Pg. 720, 1995.

supplier list

Sinoway Chemical Co., Ltd.: Tel:; Address: 16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

Jinan Laien Chemical Co., Ltd: Tel:86-543-5081965; Address: 28 Gongye Rd. South, Jinan High-tech Zone, Jinan, China

Beijing huafeng united technology co.,ltd: Tel:; Address: NO.18 Jianguo RD, Chaoyang district, Beijing, China

Zhejiang Chemline industuries Co., Ltd.: Tel:; Address: Rm.1905-1907, Eastcom Bldg., 398 Wensan Road, Hangzhou, 310013, China

Taizhou Xingcheng Chempharm Co., Ltd.: Tel:+86-(576)-88886292, 88525005; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road, Taizhou, Zhejiang 318000,

Taizhou Crene Chempharm Co., Ltd.: Tel:+86-(576)-88813233; Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000,

Nanjing Samwon International Limited: Tel:+86-(25)-84873444; Address: 1108, BLDG B, New Century Plaza, No 1, South Taiping Rd., Nanjing, Jiangsu 210002,

Beijing Huikang Boyuan Chemical Tech Co.,LTD: Tel:+86-10-68862197，68867502; Address: No.7 Haiying Road,Science City,Fengtai District,Beijing,China

ZHONGBEI NORTHLAND BIO-CHEM INDUSTRY CO., LTD.: Tel:+86-452-6197139; Address: SONGLING DISTRICT, JIAGEDAQI CITY, DAXINGANLING, HEILONGJIANG PROVINCE, CHINA

Guangzhou WeiBo Chemical Co., Ltd.: Tel:020-33640779 32416961; Address: NO.1002-39,jinbi building,shijinshicha road,baiyun district,guanghzou city

Sinosource Pharma Limited: Tel:+86-(20)-85581896, 33698005; Address: 1-19L, Canada Garden, Tianhe, Guangzhou, Guangdong 510665,

Xin xing Chemical Co.,LTD: Tel:86-516-88957771; Address: No79 # Xin bei Rd Xin yi city Jiang su Province China

Xingcheng Chemphar Co.,Ltd.: Tel:0086-576-88559905; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China

HangZhou Puris Biotechnology Ltd.: Tel:86-571-18663102648; Address: Wantang RD262, Hangzhou,Zhejiang P.R,China

Tacrolimus monohydrate cas no:109581-93-3

Directory

supplier list