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Fumaric acid cas no:110-17-8

Synonyms: trans-2-Butenedioic acid

Identification
NameFumaric acid
CAS110-17-8
Synonymstrans-2-Butenedioic acid
EINECS(EC#)203-743-0
Molecular FormulaC4H4O4
Molecular Weight116.07
Chemical Properties
Appearancewhite powder or colourless crystals
Safety Data

Hazard Xi:Irritant
Risk R36
Safety

Hazard Codes:?IrritantXi
Risk Statements: 36?
R36:Irritating to eyes.
Safety Statements: 26?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: UN 9126
WGK Germany: 1
RTECS: LS9625000
Fumaric acid converts to the irritant maleic anhydride, upon partial combustion.

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Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 100mg/kg (100mg/kg) ? National Technical Information Service. Vol. AD277-689,
mouse LD50 unreported 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Toksikologicheskii Vestnik. Vol. (2), Pg. 25, 1994.
rabbit LDLo oral 5gm/kg (5000mg/kg) ? Industrial and Engineering Chemistry. Vol. 15, Pg. 628, 1923.
rat LD50 oral 9300mg/kg (9300mg/kg) ? Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977.
rat LD50 unreported 6800mg/kg (6800mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: EXCITEMENT
Toksikologicheskii Vestnik. Vol. (2), Pg. 25, 1994.
rat LDLo intraperitoneal 587mg/kg (587mg/kg) GASTROINTESTINAL: OTHER CHANGES

LIVER: OTHER CHANGES

BLOOD: HEMORRHAGE
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 35, Pg. 298, 1946.

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