Isoamyl nitrite cas no:110-46-3

NameIsoamyl nitrite
CAS110-46-3
SynonymsIsopentylalcohol, nitrite (8CI);3-Methylbutanol nitrite;3-Methylbutyl nitrite;Amylnitrite;Aspiral;NSC 7903;Nitramyl;Nitrous acid, isopentyl ester;Pentyl nitrite;Vaporole;
EINECS(EC#)203-770-8
Molecular FormulaC₅H₁₁NO₂
Molecular Weight117.15

Appearanceyellow liquid
refractive index1.3855-1.3875
storage temp2-8°C
Sensitive Air & Light Sensitive

Hazardclass3

Hazard F:Flammable
Risk R11;R20/22
Safety Hazard Codes:F,Xn
Risk Statements:11-20/22
11:Highly Flammable
20/22:Harmful by inhalation and if swallowed
Safety Statements:16-24-46
16:Keep away from sources of ignition - No smoking
24:Avoid contact with skin
46:If swallowed, seek medical advice immediately and show this container or label
RIDADR:UN 1113 3/PG 2
WGK Germany:1
HazardClass:3
PackingGroup:II

CHEMICAL IDENTIFICATION

RTECS NUMBER :

NT0187500

CHEMICAL NAME :

Isopentyl alcohol, nitrite

CAS REGISTRY NUMBER :

110-46-3

BEILSTEIN REFERENCE NO. :

0969510

LAST UPDATED :

199701

DATA ITEMS CITED :

12

MOLECULAR FORMULA :

C5-H11-N-O2

MOLECULAR WEIGHT :

117.17

WISWESSER LINE NOTATION :

ONO2Y

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

505 mg/kg

TOXIC EFFECTS :

Behavioral - general anesthetic

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

716 ppm/4H

TOXIC EFFECTS :

Behavioral - altered sleep time (including change in righting reflex) Behavioral - excitement Lungs, Thorax, or Respiration - cyanosis

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1430 ppm/30M

TOXIC EFFECTS :

Behavioral - changes in motor activity (specific assay)

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

130 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

51 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

167 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold

MUTATION DATA

TYPE OF TEST :

Sister chromatid exchange

TEST SYSTEM :

Rodent - hamster Ovary

DOSE/DURATION :

16 mg/L

REFERENCE :

EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83996 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 33 (estimated)