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Diethanolamine cas no:111-42-2

Synonyms: 2,2-Iminodiethanol; diolamine; Bis(beta-hydroxyethyl)amine; DEA; 2,2'-Iminodiethanol

Identification
NameDiethanolamine
CAS111-42-2
Synonyms2,2-Iminodiethanol; diolamine; Bis(beta-hydroxyethyl)amine; DEA; 2,2'-Iminodiethanol
EINECS(EC#)203-868-0
Molecular FormulaC4H11NO2
Molecular Weight105.14
Chemical Properties
Appearancesolid or viscous liquid with an amine odour
refractive index1.475-1.479
storage tempStore at RT
Sensitive Hygroscopic
Safety Data

Hazard Xn:Harmful
Risk R22;R38;R41;R48/22
Safety

Safety Information of Diethanolamine (CAS No.111-42-2):
Hazard Codes:?HarmfulXn
Risk Statements: 22-38-41-48/22?
R22:Harmful if swallowed.?
R38:Irritating to skin.?
R41:Risk of serious damage to the eyes.?
R48/22:Harmful: danger of serious damage to health by prolonged exposure if swallowed.
Safety Statements: 26-36/37/39-46
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S46:If swallowed, seek medical advice immediately and show this container or label.
RIDADR: 3267
WGK Germany: 1
RTECS: KL2975000
F: 3
PackingGroup: II
Hazardous Substances Data: 111-42-2(Hazardous Substances Data)


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 2gm/kg (2000mg/kg) ? "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 5, Pg. 197, 1986.
guinea pig LD50 skin 11900uL/kg (11.9mL/kg) ? National Technical Information Service. Vol. OTS0516742,
mammal (species unspecified) LDLo oral 3gm/kg (3000mg/kg) ? National Technical Information Service. Vol. OTS0520710,
mouse LD50 intraperitoneal 210mg/kg (210mg/kg) ? National Technical Information Service. Vol. OTS0516742,
mouse LD50 oral 3300mg/kg (3300mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 29(11), Pg. 25, 1964.
rabbit LD50 oral 2200mg/kg (2200mg/kg) ? Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70.Vol. 2, Pg. 289, 1968.
rabbit LD50 skin 7640uL/kg (7.64mL/kg) BEHAVIORAL: ATAXIA

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"

MUSCULOSKELETAL: OTHER CHANGES
National Technical Information Service. Vol. OTS0516797,
rat LD50 intramuscular 1500mg/kg (1500mg/kg) ? Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70.Vol. 2, Pg. 289, 1968.
rat LD50 intraperitoneal 120mg/kg (120mg/kg) ? Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70.Vol. 2, Pg. 289, 1968.
rat LD50 intravenous 778mg/kg (778mg/kg) ? Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70.Vol. 2, Pg. 289, 1968.
rat LD50 oral 620uL/kg (0.62mL/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: TREMOR

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
National Technical Information Service. Vol. OTS0516797,
rat LD50 subcutaneous 2200mg/kg (2200mg/kg) ? Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70.Vol. 2, Pg. 289, 1968.

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