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Metformin hydrochloride cas no:1115-70-4

Synonyms: Diaformin;Dialon;Diformin;Diformin Retard;Dimefor;Fornidd;Geamet;Glucomin;Glucomine;Gluconil;Glucophage;Glucophage 850;Glucophage Forte;Glucophage Retard;Glucophage SR;Glufor;Gluformin;Glumeformin;Glumetza;Glumin;Glupermin;Glyceriphage;Glyciphage;Glycon;Metomin;Miformin;N,N-Dimethylbiguanide hydrochloride;N,N-Dimethylbiguanidinium chloride;N1,N1-Dimethylbiguanide hydrochloride;Orabet;Siamformet;Walaphage;Biguanide, 1,1-dimethyl-, monohydrochloride(8CI);Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride (9CI);1,1-Dimethylbiguanide hydrochloride;

Identification
NameMetformin hydrochloride
CAS1115-70-4
SynonymsDiaformin;Dialon;Diformin;Diformin Retard;Dimefor;Fornidd;Geamet;Glucomin;Glucomine;Gluconil;Glucophage;Glucophage 850;Glucophage Forte;Glucophage Retard;Glucophage SR;Glufor;Gluformin;Glumeformin;Glumetza;Glumin;Glupermin;Glyceriphage;Glyciphage;Glycon;Metomin;Miformin;N,N-Dimethylbiguanide hydrochloride;N,N-Dimethylbiguanidinium chloride;N1,N1-Dimethylbiguanide hydrochloride;Orabet;Siamformet;Walaphage;Biguanide, 1,1-dimethyl-, monohydrochloride(8CI);Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride (9CI);1,1-Dimethylbiguanide hydrochloride;
EINECS(EC#)214-230-6
Molecular FormulaC4H12ClN5
Molecular Weight165.62
Chemical Properties
Appearancecrystalline solid
Safety Data

Hazard Xn:Harmful
Risk R22;R36/38
Safety

Hazard Codes:?HarmfulXn
Risk Statements: 22-36/38
R22:Harmful if swallowed.?
R36/38:Irritating to eyes and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: DU1800000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intramuscular 200mg/kg (200mg/kg) ? Toxicology and Applied Pharmacology. Vol. 2, Pg. 474, 1960.
guinea pig LD50 intraperitoneal 200mg/kg (200mg/kg) ? Toxicology and Applied Pharmacology. Vol. 2, Pg. 474, 1960.
guinea pig LD50 oral 500mg/kg (500mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
guinea pig LD50 subcutaneous 150mg/kg (150mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
mouse LD50 intraperitoneal 420mg/kg (420mg/kg) ? Drugs in Japan Vol. 6, Pg. 841, 1982.
mouse LD50 intravenous 180mg/kg (180mg/kg) ? U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04012,
mouse LD50 oral 1450mg/kg (1450mg/kg) ? Drugs in Japan Vol. 6, Pg. 841, 1982.
mouse LD50 subcutaneous 225mg/kg (225mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
rabbit LD50 oral 350mg/kg (350mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
rabbit LD50 subcutaneous 150mg/kg (150mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
rat LD50 intraperitoneal 500mg/kg (500mg/kg) ? French Demande Patent Document. Vol. #2220256,
rat LD50 oral 1gm/kg (1000mg/kg) ? "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 934, 1989.
rat LD50 subcutaneous 300mg/kg (300mg/kg) ? "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 934, 1989.

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Daebong Incheon factory
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INFA S.P.A.
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SINOCHEM NINGBO LTD.
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Hunan Changsha Chemfar Economy & Trade Corp. Ltd.
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Hangzhou Starshine Pharmaceutical Co., LTD
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Shouguang Fukang Pharmaceutical Co.,Ltd.
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Ancheng Pharma Limited
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Maxpharm Group
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Kingland Chemicals Company Limited
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Suntin MediPharma Co. Ltd.
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Jiacheng Chem Enterprises
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N-Techem International Co.Ltd.
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Shandong Liangzou Mineral Industry Group company
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Address: 428 DAIXI THIRD ROAD ZOUPING COUNTY ,SHANDONG PROVINCE ,CHINA

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