Calcipotriene cas no:112965-21-6
Synonyms: 9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol,24-cyclopropyl-, (1a,3b,5Z,7E,22E,24S)- (9CI);Calciptriol;Daivonex;Dovonex;MC 903;PRI 2201;Psorcutan;
NameCalcipotriene
CAS112965-21-6
Synonyms9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol,24-cyclopropyl-, (1a,3b,5Z,7E,22E,24S)- (9CI);Calciptriol;Daivonex;Dovonex;MC 903;PRI 2201;Psorcutan;
Molecular FormulaC27H40O3
Molecular Weight412.61
Appearancewhite crystalline solid
storage tempStore in original container in a cool dark place.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LD50 |
skin |
> 1500ug/kg (1.5mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: NAUSEA OR VOMITING
MUSCULOSKELETAL: OTHER CHANGES |
Journal of Toxicological Sciences. Vol. 21(Suppl, |
| man |
TDLo |
skin |
11gm/kg/11W-I (11000mg/kg) |
? |
British Medical Journal. Vol. 306, Pg. 896, 1993. |
| rat |
LD50 |
skin |
> 15mg/kg (15mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA |
Journal of Toxicological Sciences. Vol. 21(Suppl, |
| rat |
LD50 |
subcutaneous |
2190ug/kg (2.19mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" |
Journal of Toxicological Sciences. Vol. 21(Suppl, |
| women |
TDLo |
skin |
10gm/kg/6W-I (10000mg/kg) |
? |
British Medical Journal. Vol. 306, Pg. 896, 1993. |
