1-Propanamine,3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl- cas no:113-53-1
Synonyms: Dibenzo[b,e]thiepin-D11(6H),g-propylamine, N,N-dimethyl-(7CI,8CI);Dibenzo[b,e]thiepin, 1-propanamine deriv.;Dosulepin;Dosulepine;Dothep;Dothiepin;IZ 914;Prothiaden;Prothiadene;
Name1-Propanamine,3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-
CAS113-53-1
SynonymsDibenzo[b,e]thiepin-D11(6H),g-propylamine, N,N-dimethyl-(7CI,8CI);Dibenzo[b,e]thiepin, 1-propanamine deriv.;Dosulepin;Dosulepine;Dothep;Dothiepin;IZ 914;Prothiaden;Prothiadene;
EINECS(EC#)204-031-2
Molecular FormulaC19H21NS
Molecular Weight295.47
AppearancePale yellow low melting solid
storage tempRefrigerator
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety
Human systemic effects by ingestion: central nervous system including coma, and cardiac arrhythmia. Mutation data reported. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.
Safety information of Dosulepin hydrochloride (CAS NO.113-53-1):
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
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cyt-mus-ipr 100 mg/kg
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ACNSAX Activitas Nervosa Superior. 15 (1973),114. |
| 2. |
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dlt-mus-ipr 150 mg/kg
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ACNSAX Activitas Nervosa Superior. 15 (1973),114. |
| 3. |
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orl-inf TDLo:100 mg/kg:CNS,CVS
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BMJOAE British Medical Journal. 288 (1984),1800. |
| 4. |
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orl-wmn TDLo:4500 µg/kg:CNS
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BMJOAE British Medical Journal. 2 (1977),97. |
