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1H-Pyrazol-5-amine,3-methyl-1-phenyl- cas no:1131-18-6

Synonyms: Pyrazole,5-amino-3-methyl-1-phenyl- (6CI,7CI,8CI);1-Phenyl-3-methyl-5-aminopyrazole;3-Amino-5-methyl-2-phenyl-2H-pyrazole;3-Methyl-1-phenyl-1H-pyrazol-5-amine;3-Methyl-1-phenyl-5-pyrazolamine;3-Methyl-1-phenylpyrazol-5-amine;5-Methyl-2-phenyl-2H-pyrazol-3-ylamine;

Identification
Name1H-Pyrazol-5-amine,3-methyl-1-phenyl-
CAS1131-18-6
SynonymsPyrazole,5-amino-3-methyl-1-phenyl- (6CI,7CI,8CI);1-Phenyl-3-methyl-5-aminopyrazole;3-Amino-5-methyl-2-phenyl-2H-pyrazole;3-Methyl-1-phenyl-1H-pyrazol-5-amine;3-Methyl-1-phenyl-5-pyrazolamine;3-Methyl-1-phenylpyrazol-5-amine;5-Methyl-2-phenyl-2H-pyrazol-3-ylamine;
EINECS(EC#)214-463-3
Molecular FormulaC10H11N3
Molecular Weight173.21
Chemical Properties
refractive index1.624
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes of 1-Phenyl-3-methyl-5-aminopyrazole (CAS NO.1131-18-6): IrritantXi,HarmfulXn
Risk Statements: 36/37/38-20/21/22 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 1300mg/kg (1300mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 03FEB1981,
mouse LDLo intraperitoneal 800mg/kg (800mg/kg)   Farmakologiya i Toksikologiya Vol. 27, Pg. 295, 1964.
rabbit LD50 oral 1gm/kg (1000mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 03FEB1981,
rat LD50 oral 2500mg/kg (2500mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 03FEB1981,

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