N-Carbobenzyloxyglycine cas no:1138-80-3

NameN-Carbobenzyloxyglycine
CAS1138-80-3
SynonymsBenzyloxycarbonylglycine;Carbobenzoxyl glycine;Z-Gly;N-Carboxyglycine N-benzyl ester;Glycine, N-[ (phenylmethoxy)carbonyl]-;N-Carbobenzoxyglycine;(Cbz)gly;glycine, N-[(phenylmethoxy)carbonyl]-;N-[(benzyloxy)carbonyl]glycine;N-(benzyloxycarbonyl)glycine;2-phenylmethoxycarbonylaminoacetic acid;N-CBZ-glycine;Carbobenzoxyglycine;Carbobenzyloxyglycine;2-phenylmethoxycarbonylaminoacetate;Glycine, N-carboxy-, N-benzyl ester;Z-Gly-OH;CBZ-Glycine;Cbz Glycine;Z-Glycine;Cbz-Gly-OH;N-benzyloxycarbonylglycine;
EINECS(EC#)214-516-0
Molecular FormulaC₁₀H₁₁NO₄
Molecular Weight209.19864

Appearanceslightly beige powder
storage tempStore at RT.

Hazard Not regulated
Risk R62
Safety Poison by intravaginal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS.
HS Code 29242995

CHEMICAL IDENTIFICATION

RTECS NUMBER :

MB9129000

CHEMICAL NAME :

Glycine, N-carboxy-, N-benzyl ester

CAS REGISTRY NUMBER :

1138-80-3

BEILSTEIN REFERENCE NO. :

0526877

LAST UPDATED :

199701

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C10-H11-N-O4

MOLECULAR WEIGHT :

209.22

WISWESSER LINE NOTATION :

QVN1R&1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravaginal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

380 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 ** REPRODUCTIVE DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

280 mg/kg

SEX/DURATION :

female 28 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :

JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 70,60,1981

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intravaginal

DOSE :

280 mg/kg

SEX/DURATION :

female 28 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :

JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 70,60,1981