Phenformin cas no:114-86-3
Synonyms: Biguanide,1-phenethyl- (6CI,8CI);(Phenylethyl)biguanide;1-Phenethylbiguanide;Cronoformin;Debeone;Diabis;Dibiraf;Dibotin;Fenfoduron;Fenformin;Fenormin;Glukopostin;Glyphen;Phenethylbiguanide;
NamePhenformin
CAS114-86-3
SynonymsBiguanide,1-phenethyl- (6CI,8CI);(Phenylethyl)biguanide;1-Phenethylbiguanide;Cronoformin;Debeone;Diabis;Dibiraf;Dibotin;Fenfoduron;Fenformin;Fenormin;Glukopostin;Glyphen;Phenethylbiguanide;
EINECS(EC#)204-057-4
Molecular FormulaC10H15N5
Molecular Weight205.26
Appearancewhite powder
refractive index1.62
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Hazard Xn: Harmful;
Risk R22
Safety
Poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.Safety information of Phenformin (CAS NO.114-86-3):
Hazard Codes: 
Xn
Risk Statements: 22
R22:Harmful if swallowed.
Safety Statements: 36
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: DU2200000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| guinea pig |
LD50 |
subcutaneous |
16mg/kg (16mg/kg) |
|
Medicina Experimentalis. Vol. 8, Pg. 237, 1963. |
| guinea pig |
LDLo |
intravenous |
30mg/kg (30mg/kg) |
|
"Hemoperfusion: Kidney and Liver Support and Detoxification, Proceedings of the International Symposium, Haifa, 1979," Sideman, S., and T.M.S. Chang, eds., Multiple parts, New York, Hemisphere Pub. Corp., 1980-Vol. 1, Pg. 337, 1980. |
| mouse |
LD50 |
intraperitoneal |
140mg/kg (140mg/kg) |
|
Bollettino Chimico Farmaceutico. Vol. 97, Pg. 396, 1958. |
| mouse |
LD50 |
oral |
450mg/kg (450mg/kg) |
|
Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 42, Pg. 236, 1985. |
| rat |
LD50 |
oral |
650mg/kg (650mg/kg) |
|
Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 42, Pg. 236, 1985. |
