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L-Serine,O-(2-diazoacetyl)- cas no:115-02-6

Synonyms: L-Serine,diazoacetate (ester) (9CI); Serine, diazoacetate (ester), L- (6CI,8CI);Azaserin; Azaserine; CI 337; CN 15757; L-Azaserine; NSC 742;O-Diazoacetyl-L-serine; P 165

Identification
NameL-Serine,O-(2-diazoacetyl)-
CAS115-02-6
SynonymsL-Serine,diazoacetate (ester) (9CI); Serine, diazoacetate (ester), L- (6CI,8CI);Azaserin; Azaserine; CI 337; CN 15757; L-Azaserine; NSC 742;O-Diazoacetyl-L-serine; P 165
EINECS(EC#)204-061-6
Molecular FormulaC5H7 N3 O4
Molecular Weight 173.15
Chemical Properties
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T: Toxic;
Risk R25
Safety

Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
 

Hazard Codes: T
Risk Statements:
25:  Toxic if swallowed
40:  Limited evidence of a carcinogenic effect
Safety Statements:
36:  Wear suitable protective clothing 
37:  Wear suitable gloves
39:  Wear eye/face protection
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53:  Avoid exposure - obtain special instruction before use


Toxicity
1.    

mma-sat 200 ng/plate

    PNASA6    Proceedings of the National Academy of Sciences of the United States of America. 72 (1975),5135.
2.    

mmo-bcs 500 µmol/L

    EXPEAM    Experientia. 39 (1983),530.
3.    

orl-rat LD50:170 mg/kg

    CANCAR    Cancer. 10 (1957),889.
4.    

ipr-rat LD50:70 mg/kg

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 94 (1957),27.
5.    

orl-mus LD50:150 mg/kg

    CANCAR    Cancer. 10 (1957),889.
6.    

ipr-mus LD50:100 mg/kg

    CANCAR    Cancer. 10 (1957),889.
7.    

scu-mus LD50:50 mg/kg

    85GDA2    CRC Handbook of Antibiotic Compounds, Volumes 1-9. 4 (1)(1980),432.
8.    

ivn-mus LD50:62 mg/kg

    85ERAY    Antibiotics: Origin, Nature, and Properties. 2 (1978),1249.
9.    

ivn-dog LDLo:30 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 22 (1972),595.

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Tel:86-21-62277841
Address: B-7C,1068, Xikang Road, Shanghai, China

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