2,2,2-Trichloroethanol cas no:115-20-8
Synonyms: Trichloroethanol;
Trichloroethylalcohol
Name2,2,2-Trichloroethanol
CAS115-20-8
SynonymsTrichloroethanol;
Trichloroethylalcohol
EINECS(EC#)204-071-0
Molecular FormulaC2H3Cl3O
Molecular Weight149.4
AppearanceClear almost colorless liquid.
refractive index1.4885-1.4905
storage tempKeep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Sensitive Hygroscopic
Hazard Xn:Harmful;
Risk R22;R41
Safety
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and rectal routes. Human mutation data reported. Explosive reaction with concentrated sodium hydroxide solutions. When heated to decomposition it emits toxic fumes of Cl−.
Hazard Codes: Xn .gif)
Risk Statements: 22-41 (22: Harmful if swallowed 41: Risk of serious damage to eyes)
Safety Statements: 26-39 (26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 39: Wear eye/face protection)
RIDADR: 1760
WGK Germany: 1
F: 3-21
PackingGroup: III
HS Code: 29055910
HS Code 29055910
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LDLo |
oral |
500mg/kg (500mg/kg) |
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Current Researches in Anesthesia and Analgesia. Vol. 17, Pg. 258, 1938. |
| rabbit |
LDLo |
intravenous |
50mg/kg (50mg/kg) |
BEHAVIORAL: SLEEP |
Journal of Pharmacology and Experimental Therapeutics. Vol. 63, Pg. 453, 1938. |
| rabbit |
LDLo |
rectal |
500mg/kg (500mg/kg) |
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Current Researches in Anesthesia and Analgesia. Vol. 17, Pg. 258, 1938. |
| rat |
LDLo |
intraperitoneal |
300mg/kg (300mg/kg) |
BEHAVIORAL: GENERAL ANESTHETIC |
Journal of Pharmacology and Experimental Therapeutics. Vol. 63, Pg. 453, 1938. |
| rat |
LDLo |
oral |
500mg/kg (500mg/kg) |
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Current Researches in Anesthesia and Analgesia. Vol. 17, Pg. 258, 1938. |
RTECS: KM3850000
