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Tris(2-chloroethyl) phosphate cas no:115-96-8

Synonyms: Tris(β-chloroethyl) phosphate; TCEP

Identification
NameTris(2-chloroethyl) phosphate
CAS115-96-8
SynonymsTris(β-chloroethyl) phosphate; TCEP
EINECS(EC#)204-118-5
Molecular FormulaC6H12Cl3O4P
Molecular Weight285.49
Chemical Properties
Appearanceodorless clear liquid
refractive index1.471-1.473
storage tempKeep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Safety Data

Hazard Xn:Harmful
Risk R22;R40;R51/53
Safety

Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. A skin and eye irritant. Combustible when exposed to heat or flame. When heated to decomposition it emits very toxic fumes of POx and Cl?. See also PHOSPHATES, CHLORIDES, and ESTERS.
Hazard Codes: Xn,N
Risk Statements: 22-40-51/53
22:? Harmful if swallowed?
40:? Limited evidence of a carcinogenic effect?
51/53:? Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment??
Safety Statements: 36/37-61
36/37:? Wear suitable protective clothing and gloves?
61:? Avoid release to the environment. Refer to special instructions safety data sheet??
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
RTECS: KK2450000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 1866mg/kg (1866mg/kg) ? National Technical Information Service. Vol. AD-A067-313,
mouse LDLo intraperitoneal 250mg/kg (250mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 7, Pg. 396, 1955.
rabbit LDLo skin 2gm/kg (2000mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: OTHER CHANGES

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
National Technical Information Service. Vol. OTS0517716,
rat LD50 oral 1230mg/kg (1230mg/kg) ? Bulletin of Environmental Contamination and Toxicology. Vol. 17, Pg. 720, 1977.

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