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Methanesulfonamide,N-[4-[2-[methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]- cas no:115256-11-6

Synonyms: Dofetilida;Tikosyn;UK 68798;Dofetilidum;Tikosyn;UK 68,798;UNII-R4Z9X1N2ND;beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide;CHEBI:4681;

Identification
NameMethanesulfonamide,N-[4-[2-[methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-
CAS115256-11-6
SynonymsDofetilida;Tikosyn;UK 68798;Dofetilidum;Tikosyn;UK 68,798;UNII-R4Z9X1N2ND;beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide;CHEBI:4681;
Molecular FormulaC19H27N3O5S2
Molecular Weight441.56
Chemical Properties
AppearanceOff-white or yellowish crystalline powder
refractive index1.613
storage tempStore in original container in a cool dark place.
Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PB0478000
CHEMICAL NAME :
Methanesulfonamide, N-(4-(2-(methyl(2-(4-((methylsulfonyl)amino)phenoxy)e thyl)amino)ethyl) phenyl)-
CAS REGISTRY NUMBER :
115256-11-6
LAST UPDATED :
199806
DATA ITEMS CITED :
3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
22050 ug/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 53,168,1996
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
11025 ug/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 53,168,1996
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
44100 ug/kg
SEX/DURATION :
female 14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 53,168,1996

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