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3,3',4',5,7-pentahydroxyflavone cas no:117-39-5

Synonyms: 3,3,4,5,7-Pentahydroxyflavone (pract); Quercetin

Identification
Name3,3',4',5,7-pentahydroxyflavone
CAS117-39-5
Synonyms3,3,4,5,7-Pentahydroxyflavone (pract); Quercetin
EINECS(EC#)204-187-1
Molecular FormulaC15H10O7
Molecular Weight302.24
Chemical Properties
AppearanceYellow to green yellow crystalline powde
refractive index1.767
storage tempStore at 0-5°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T:Toxic
Risk R25;R40
Safety

Hazard Codes?of Quercetin (CAS NO.117-39-5):?ToxicT,IrritantXi
Risk Statements:?25-36/37/38?
R25: Toxic if swallowed.?
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements:?45-36-26?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36: Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR:?2811
RTECS:?LK8750000
HazardClass:?6.1(b)
PackingGroup:?III


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 3gm/kg (3000mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64, Pg. 186, 1968.
mouse LD50 intravenous 18mg/kg (18mg/kg) ? U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02589,
mouse LD50 oral 159mg/kg (159mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951.
mouse LD50 subcutaneous 97mg/kg (97mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951.
rabbit LD50 intravenous 100mg/kg (100mg/kg) ? FAO Nutrition Meetings Report Series. Vol. 46A, Pg. 18, 1969.
rat LD50 oral 161mg/kg (161mg/kg) ? Reviews of Environmental Contamination and Toxicology. Vol. 113, Pg. 47, 1990.

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