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10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)- cas no:117-89-5

Synonyms: Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)- (6CI,8CI);2-Trifluoromethyl-10-[3'-(1-methyl-4-piperazinyl)propyl]phenothiazine;Flurazine; NSC 17474; RP 7623; TFP; Trifluoperazin; Trifluoperazine;Trifluoromethylperazine; Trifluoroperazine; Trifluperazine; Triflurin;Triperazine

Identification
Name10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
CAS117-89-5
SynonymsPhenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)- (6CI,8CI);2-Trifluoromethyl-10-[3'-(1-methyl-4-piperazinyl)propyl]phenothiazine;Flurazine; NSC 17474; RP 7623; TFP; Trifluoperazin; Trifluoperazine;Trifluoromethylperazine; Trifluoroperazine; Trifluperazine; Triflurin;Triperazine
EINECS(EC#)204-219-4
Molecular FormulaC21H24 F3 N3 S
Molecular Weight407.5
Chemical Properties
Appearancewhite to yellowish crystalline powder
Safety Data

Hazard UN NO.
Safety

Poison by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of F, NOx, and SOx. Used as an antipsychotic and sedative. See also FLUORIDES.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 120mg/kg (120mg/kg)   Neuropharmacology. Vol. 9, Pg. 235, 1970.
mouse LD50 intravenous 29mg/kg (29mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
mouse LD50 oral 1350mg/kg (1350mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.

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